1. Product Overview and Specifications

Key Differentiators: Superior thermal stability compared to pyridine derivatives, with enhanced solubility in polar solvents. Available in 1kg to 200kg industrial packaging.

2. Key Applications and Industrial Uses

Pharmaceutical Intermediate

• Core precursor for P2Y1 receptor antagonists (e.g., benzothiazolyl hydroxyindolinyl phenylurea)
• Building block for anti-inflammatory analgesics via Schiff base formation

Corrosion Science

• Effective corrosion inhibitor for aluminum and copper alloys in acidic environments (pH 2-5)
• Forms stable metal coordination complexes at concentrations ≥0.5mM

Advanced Material Synthesis

• Ligand for transition metal catalysts in organic cross-coupling reactions
• Functional group modifier in polymer coatings

3. Synthesis Methods and Technical Insights

Optimized Production Protocols

1. One-Pot Synthesis: Achieves 82-85% yield via controlled aminolysis of 2,3-dihalopyridines
2. Catalytic Hydroxylation: Palladium-mediated process reduces byproducts to <3%
3. Patent-Protected Methods: CN202011290175.2 (high-purity crystallization) and CN201710133751.4 (solvent recovery systems)

Quality Control: HPLC purity verification (USP <621>), residual solvent analysis per ICH Q3C guidelines.

4. Case Studies and Client Implementations

Case 1: Pharmaceutical Manufacturer (Shanghai)

• Challenge: Scale-up of anticoagulant API batch production from 10kg to 500kg
• Solution: Customized synthesis with 99.7% purity and reduced Pd catalyst loading
• Outcome: 30% cost reduction, compliance with FDA CMC requirements

Case 2: Specialty Chemicals Supplier (Hubei)

• Challenge: Develop non-toxic alternative to chromate corrosion inhibitors
• Solution: 3-Amino-2-hydroxypyridine-based formulation at 0.8% w/v concentration
• Outcome: 94% corrosion inhibition efficiency (ASTM G31-12a), RoHS compliance

5. Safety and Handling Guidelines

6. Procurement and Custom Solutions

Available Configurations:
– Standard: 25kg fiber drums (GMP-compliant)
– Bulk: ISO tank containers (1,000kg+ quantities)
– Research: 100mg-5g aliquots with COA

Technical Support:
Our chemical engineers provide:
– Process optimization consultations
– Regulatory documentation preparation
– Application-specific formulation development

Contact Our Team:
Email: info@vivalr.com
Tel: (86) 15866781826
Office Hours: Mon-Fri 08:30-17:30 CST