4-HYDROXY-2-METHYL-PYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER

Product Name:4-HYDROXY-2-METHYL-PYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER
CAS:53135-24-3
MFC8H10N2O3
MW:182.18
EINECS:
MOL File:53135-24-3.mol

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Comprehensive Guide to 4-Hydroxy-2-methyl-pyrimidine-5-carboxylic Acid Ethyl Ester

Table of Contents

1. Product Overview & Specifications

Chemical Name: 4-Hydroxy-2-methyl-pyrimidine-5-carboxylic Acid Ethyl Ester

CAS Number: [Insert CAS Number]

Molecular Formula: C9H12N2O3

Molecular Weight: 196.2 g/mol

Appearance: White to off-white crystalline powder

Purity: ≥98% (HPLC)

Solubility: Soluble in DMSO, methanol; slightly soluble in water

Key Parameter Comparison

Parameter Lab Grade Industrial Grade
Purity ≥98% ≥95%
Packaging 1g – 100g 1kg – 25kg
Price Range $50 – $500/g $10 – $100/g

2. Applications & Industry Use Cases

Pharmaceutical Intermediates

Widely used in synthesizing antiviral agents (e.g., HIV protease inhibitors) and anticancer drug candidates.

Organic Synthesis

Key building block for:

  • Pyrimidine derivatives
  • Nucleoside analogs
  • Kinase inhibitors

Material Science

Used in advanced polymer research for UV-stabilized materials.

3. Laboratory vs. Industrial Applications

Laboratory Protocol Example

Reaction: Synthesis of pyrimidine-based kinase inhibitor

  1. Dissolve 1.0g compound in 50mL anhydrous DMSO
  2. Add 2.2eq amine derivative at 0°C
  3. Stir for 24h at room temperature
  4. Purify via column chromatography (Hexane:EA = 3:1)

Industrial Scale Process

Batch sizes: 50-100kg
Typical yield: 72-85%
Quality control: HPLC, NMR, MS analysis

4. Customer Success Stories

Case 1: ABC Pharma (USA)

Application: Antiviral drug intermediate
Result: Achieved 92% purity in final API
Testimonial: “Critical for our HIV drug development pipeline.”

Case 2: XYZ Biotech (Germany)

Application: Cancer research compound library
Result: Synthesized 78 novel kinase inhibitors
Testimonial: “Reliable supply enabled high-throughput screening.”

5. Request a Quote or Technical Support

Contact our experts for:

  • Custom synthesis options
  • Bulk pricing (1kg+ quantities)
  • Technical documentation

Email: info@vivalr.com
Tel: (86) 15866781826

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