Dimethyl 2,6-Pyridinedicarboxylate: Comprehensive User Guide
Table of Contents
- 1. Product Overview & Specifications
- 2. Applications & Use Cases
- 3. Industry Case Studies
- 4. Client Success Stories
- 5. Request a Quote
1. Product Overview & Specifications
Dimethyl 2,6-Pyridinedicarboxylate (CAS 5453-67-8) is a pyridine derivative widely used in pharmaceutical intermediates, polymer synthesis, and agrochemicals. Key specifications include:
| Parameter | Value |
|---|---|
| Molecular Formula | C9H9NO4 |
| Molecular Weight | 195.17 g/mol |
| Appearance | White crystalline powder |
| Purity | ≥98% (HPLC) |
| Melting Point | 92-95°C |
| Solubility | Soluble in DMSO, methanol; slightly soluble in water |
Comparative Analysis with Similar Compounds
| Compound | Reactivity | Cost Efficiency | Application Range |
|---|---|---|---|
| Dimethyl 2,6-Pyridinedicarboxylate | High | $$$ | Pharma, Polymers |
| Dimethyl Isophthalate | Medium | $$ | Polymers |
| Dimethyl Terephthalate | Low | $ | Textiles |
2. Applications & Use Cases
Pharmaceutical Intermediates
Used in synthesizing antituberculosis drug precursors like PA-824. Enables precise carboxylation reactions under mild conditions.
Polymer Chemistry
Serves as a monomer for heat-resistant polyamides in automotive components (e.g., engine covers).
Coordination Chemistry
Acts as a ligand for catalytic systems in asymmetric hydrogenation (up to 95% enantiomeric excess).
3. Industry Case Studies
Case 1: Anticancer Drug Development
A research team utilized 2,6-Pyridinedicarboxylate to create kinase inhibitors showing 80% tumor growth suppression in preclinical trials.
Case 2: High-Performance Resins
Manufacturer achieved 40% improvement in thermal stability for aerospace adhesives using this compound.
4. Client Success Stories
Client A: PharmaSynth Ltd. (Germany)
- Challenge: Low yield (45%) in API intermediate synthesis
- Solution: Optimized esterification using 2,6-Pyridinedicarboxylate
- Result: Yield increased to 78%, reduced reaction time by 35%
Client B: PolymerTech Inc. (USA)
- Challenge: Brittleness in polyamide composites
- Solution: Incorporated 1.5% 2,6-Pyridinedicarboxylate as co-monomer
- Result: 50% higher impact resistance, 20°C increase in HDT
5. Request a Quote
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