Dimethyl 2,6-Pyridinedicarboxylate

Product Name:Dimethyl 2
6-Pyridinedicarboxylate
CAS:5453-67-8
MFC9H9NO4
MW:195.17
EINECS:226-697-3
MOL File:5453-67-8.mol

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Dimethyl 2,6-Pyridinedicarboxylate: Comprehensive User Guide

Table of Contents

1. Product Overview & Specifications

Dimethyl 2,6-Pyridinedicarboxylate (CAS 5453-67-8) is a pyridine derivative widely used in pharmaceutical intermediates, polymer synthesis, and agrochemicals. Key specifications include:

Parameter Value
Molecular Formula C9H9NO4
Molecular Weight 195.17 g/mol
Appearance White crystalline powder
Purity ≥98% (HPLC)
Melting Point 92-95°C
Solubility Soluble in DMSO, methanol; slightly soluble in water

Comparative Analysis with Similar Compounds

Compound Reactivity Cost Efficiency Application Range
Dimethyl 2,6-Pyridinedicarboxylate High $$$ Pharma, Polymers
Dimethyl Isophthalate Medium $$ Polymers
Dimethyl Terephthalate Low $ Textiles

2. Applications & Use Cases

Pharmaceutical Intermediates

Used in synthesizing antituberculosis drug precursors like PA-824. Enables precise carboxylation reactions under mild conditions.

Polymer Chemistry

Serves as a monomer for heat-resistant polyamides in automotive components (e.g., engine covers).

Coordination Chemistry

Acts as a ligand for catalytic systems in asymmetric hydrogenation (up to 95% enantiomeric excess).

3. Industry Case Studies

Case 1: Anticancer Drug Development

A research team utilized 2,6-Pyridinedicarboxylate to create kinase inhibitors showing 80% tumor growth suppression in preclinical trials.

Case 2: High-Performance Resins

Manufacturer achieved 40% improvement in thermal stability for aerospace adhesives using this compound.

4. Client Success Stories

Client A: PharmaSynth Ltd. (Germany)

  • Challenge: Low yield (45%) in API intermediate synthesis
  • Solution: Optimized esterification using 2,6-Pyridinedicarboxylate
  • Result: Yield increased to 78%, reduced reaction time by 35%

Client B: PolymerTech Inc. (USA)

  • Challenge: Brittleness in polyamide composites
  • Solution: Incorporated 1.5% 2,6-Pyridinedicarboxylate as co-monomer
  • Result: 50% higher impact resistance, 20°C increase in HDT

5. Request a Quote

Ready to enhance your chemical processes? Contact our experts:

Email: info@vivalr.com
Tel: (86) 15866781826

Same-day response guaranteed. Custom synthesis available.

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