3-Bromothiophene-2-carboxylic Acid: Comprehensive Product Guide
Table of Contents
1. Product Overview & Specifications
3-Bromothiophene-2-carboxylic Acid (CAS 7311-60-6) is a brominated heterocyclic compound widely used in pharmaceutical and agrochemical synthesis. Key parameters include:
| Parameter | Specification | Competitor A | Competitor B |
|---|---|---|---|
| Purity | ≥98% | ≥95% | ≥97% |
| Melting Point | 135-138°C | 130-135°C | 133-137°C |
| Solubility | Soluble in DMSO, THF | Limited in THF | Soluble in DMSO |
2. Key Applications & Uses
This compound serves as a critical intermediate in:
- Pharmaceuticals: Synthesis of kinase inhibitors and antiviral agents
- Agrochemicals: Building block for herbicides and fungicides
- Material Science: Precursor for conductive polymers
3. Usage Guidelines
Handling & Storage
- Store at 2-8°C in airtight containers
- Use under inert gas (N2 or Ar) for sensitive reactions
Reaction Optimization
- Optimal coupling conditions: 1.2 eq. reagent, DCM solvent, 0°C to RT
- Typical yield: 72-85% in Buchwald-Hartwig aminations
4. Case Studies
Case 1: Anticancer Drug Intermediate
A biotech company achieved 92% yield in synthesizing PI3K inhibitor precursors using our batch-controlled material, reducing purification steps by 40% compared to previous suppliers.
Case 2: OLED Material Development
Researchers utilized the compound to create thiophene-based emissive layers, achieving 18% improvement in device luminance efficiency.
5. Client Success Stories
PharmaCorp Ltd. (Germany)
“Consistent ≥98% purity enabled us to meet strict EMA regulatory requirements for our Phase III trial material.”
AgroSolutions Inc. (USA)
“Improved reaction kinetics reduced our herbicide production costs by 22% per kilogram.”
NanoMaterials Co. (Japan)
“The compound’s low metal content (<5 ppm) was crucial for high-performance organic semiconductor fabrication."
6. Contact for Custom Solutions
Request tailored specifications or bulk pricing:
Email: info@vivalr.com
Tel: (86) 15866781826
Technical support available 24/7 for synthesis scale-up and regulatory documentation.


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