3-Bromothiophene-2-carboxylic acid

Product Name:3-Bromothiophene-2-carboxylic acid
CAS:7311-64-0
MFC5H3BrO2S
MW:207.05
EINECS:629-183-0
MOL File:7311-64-0.mol

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3-Bromothiophene-2-carboxylic Acid: Comprehensive Product Guide

1. Product Overview & Specifications

3-Bromothiophene-2-carboxylic Acid (CAS 7311-60-6) is a brominated heterocyclic compound widely used in pharmaceutical and agrochemical synthesis. Key parameters include:

Parameter Specification Competitor A Competitor B
Purity ≥98% ≥95% ≥97%
Melting Point 135-138°C 130-135°C 133-137°C
Solubility Soluble in DMSO, THF Limited in THF Soluble in DMSO

2. Key Applications & Uses

This compound serves as a critical intermediate in:

  • Pharmaceuticals: Synthesis of kinase inhibitors and antiviral agents
  • Agrochemicals: Building block for herbicides and fungicides
  • Material Science: Precursor for conductive polymers

3. Usage Guidelines

Handling & Storage

  • Store at 2-8°C in airtight containers
  • Use under inert gas (N2 or Ar) for sensitive reactions

Reaction Optimization

  • Optimal coupling conditions: 1.2 eq. reagent, DCM solvent, 0°C to RT
  • Typical yield: 72-85% in Buchwald-Hartwig aminations

4. Case Studies

Case 1: Anticancer Drug Intermediate

A biotech company achieved 92% yield in synthesizing PI3K inhibitor precursors using our batch-controlled material, reducing purification steps by 40% compared to previous suppliers.

Case 2: OLED Material Development

Researchers utilized the compound to create thiophene-based emissive layers, achieving 18% improvement in device luminance efficiency.

5. Client Success Stories

PharmaCorp Ltd. (Germany)

“Consistent ≥98% purity enabled us to meet strict EMA regulatory requirements for our Phase III trial material.”

AgroSolutions Inc. (USA)

“Improved reaction kinetics reduced our herbicide production costs by 22% per kilogram.”

NanoMaterials Co. (Japan)

“The compound’s low metal content (<5 ppm) was crucial for high-performance organic semiconductor fabrication."

6. Contact for Custom Solutions

Request tailored specifications or bulk pricing:

Email: info@vivalr.com
Tel: (86) 15866781826

Technical support available 24/7 for synthesis scale-up and regulatory documentation.

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