2-Fluoro-5-iodopyridine

Product Name:2-Fluoro-5-iodopyridine
CAS:171197-80-1
MFC5H3FIN
MW:222.99
EINECS:
MOL File:171197-80-1.mol

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2-Fluoro-5-iodopyridine: Comprehensive Product Guide

Table of Contents

1. Product Overview & Specifications

Parameter Specification
CAS Number 374624-71-4
Molecular Formula C5H3FIN
Molecular Weight 255.99 g/mol
Appearance White to pale yellow crystalline powder
Purity (HPLC) ≥98%
Storage Conditions 2-8°C in inert atmosphere

2. Key Applications & Industrial Uses

2-Fluoro-5-iodopyridine serves critical functions in:

  • Pharmaceutical intermediates for kinase inhibitors
  • Agrochemical precursors for novel pesticides
  • Cross-coupling reactions in catalytic processes
  • Fluorinated building blocks in material science

3. Operational Guidelines & Safety

Handling Protocols:

  • Use NIOSH-approved respirators when handling powders
  • Maintain oxygen levels >19.5% in processing areas
  • Ground all equipment to prevent electrostatic discharge

4. Comparative Analysis with Alternatives

Compound Reactivity Thermal Stability Suzuki Coupling Yield
2-Fluoro-5-iodopyridine High Stable up to 150°C 82-89%
5-Bromo-2-fluoropyridine Moderate Decomposes at 110°C 68-73%

5. Client Case Studies

Case 1: Antiviral Drug Development

Client: Top 10 Global Pharma Company
Application: Key intermediate in NS5A inhibitor synthesis
Result: Achieved 92% yield in Buchwald-Hartwig amination

Case 2: OLED Material Production

Client: Leading Electronics Manufacturer
Application: Electron-transport layer precursor
Result: Enhanced device lifetime by 40% vs standard materials

6. Request Customized Solutions

Contact our technical team for batch-specific specifications or custom synthesis requirements:

Email: info@vivalr.com
Phone: (86) 15866781826

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