2-Chloro-4-(trifluoromethyl)pyridine

Product Name:2-Chloro-4-(trifluoromethyl)pyridine
CAS:81565-18-6
MFC6H3ClF3N
MW:181.54
EINECS:617-242-3
MOL File:81565-18-6.mol

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2-Chloro-4-(trifluoromethyl)pyridine: Comprehensive Product Guide

Table of Contents

1. Product Specifications

Parameter Specification
CAS Number NA
Molecular Formula C6H3ClF3N
Molecular Weight 181.54 g/mol
Appearance Clear colorless to pale yellow liquid
Purity (HPLC) ≥98%
Storage Conditions 2-8°C in inert atmosphere

2. Key Applications

Pharmaceutical Intermediates

Critical building block for:

  • Kinase inhibitor development
  • Anticancer drug candidates
  • Neurological therapeutics

Agrochemical Synthesis

  • Herbicide intermediates
  • Insect growth regulators
  • Fungicide precursors

Material Science

  • Liquid crystal compounds
  • Polymer modification agents
  • Electronic material precursors

3. Technical Comparison

Property 2-Chloro-4-(trifluoromethyl)pyridine Similar Compounds
Reactivity High (Cl/F activation) Moderate
Thermal Stability Stable up to 150°C 120-130°C range
Synthetic Flexibility 5 reactive sites 3-4 sites typical

4. Handling Protocols

Safety Requirements

  • Use PPE: Chemical goggles, nitrile gloves
  • Operate under fume hood
  • Incompatible with strong oxidizers

Storage Best Practices

  • Maintain argon atmosphere
  • Monitor moisture content (<50 ppm)
  • Use amber glass containers

5. Client Implementations

Case 1: Pharmaceutical API Development

Client: Top 10 Global Pharma Company

Challenge: Required high-purity intermediate for Phase III oncology drug

Solution: Supplied 99.2% pure material with strict metal content control

Outcome: Successful scale-up to 500kg batches

Case 2: Crop Protection Formulation

Client: European Agrochemical Leader

Challenge: Needed stable halogenated pyridine derivative

Solution: Custom stabilization package development

Result: 18-month shelf life achieved

6. Request Customized Solutions

Contact our technical team for:

  • Bulk pricing (100kg+ quantities)
  • Custom synthesis services
  • Regulatory support documentation

Email: info@vivalr.com

Tel: (86) 15866781826

Why Choose Us:

  • ISO 9001-certified production
  • 24/7 technical support
  • Global logistics network
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