Table of Contents
Product Overview
2-Amino-5-bromo-6-methylpyridine (CAS 114875-21-1) is a brominated pyridine derivative widely used in pharmaceutical and agrochemical synthesis. Key parameters:
| Parameter | Value |
|---|---|
| Molecular Formula | C6H7BrN2 |
| Molecular Weight | 187.04 g/mol |
| Appearance | White to off-white crystalline powder |
| Purity | ≥98% (HPLC) |
| Storage | 2-8°C in inert atmosphere |
Specifications & Comparison
Competitive Analysis with Similar Compounds
| Compound | Reactivity | Cost Efficiency | Thermal Stability |
|---|---|---|---|
| 2-Amino-5-bromo-6-methylpyridine | High | $$ | Up to 150°C |
| 2-Amino-3-bromopyridine | Moderate | $ | Up to 130°C |
Applications
Pharmaceutical Intermediates
Used in synthesis of kinase inhibitors and antiviral agents due to its bromine atom’s leaving group capability.
Organic Synthesis
Key building block for Suzuki-Miyaura cross-coupling reactions to create biaryl structures.
Case Studies
Case 1: Antiviral Drug Development
A research team utilized this compound as a core intermediate in remdesivir analog synthesis, achieving 92% yield in Buchwald-Hartwig amination.
Client Examples
PharmaTech Solutions
Challenge: Required high-purity bromopyridine derivative for GLP-1 receptor agonist development.
Solution: Supplied 20kg batch with 99.2% purity under nitrogen packaging.
Result: Reduced impurity-related side reactions by 67%.
Purchasing Guide
| Factor | Evaluation Criteria |
|---|---|
| Quality | Request COA with HPLC traces |
| Lead Time | Verify supplier’s stock status |
Frequently Asked Questions
Q: What solvents are recommended for dissolution?
A: Demonstrates good solubility in DCM (50 mg/mL) and moderate solubility in ethanol (20 mg/mL).
Inquiry & Contact
For technical specifications or bulk pricing:
Email: info@vivalr.com
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