Isoquinolin-6-ol

Product Name:Isoquinolin-6-ol
CAS:7651-82-3
MFC9H7NO
MW:145.16
EINECS:231-612-8
MOL File:7651-82-3.mol

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Isoquinolin-6-ol: Comprehensive Product Guide

Table of Contents

1. Product Specifications & Comparative Analysis

Parameter Isoquinolin-6-ol Similar Compounds
CAS Number 7778-75-8 Quinolin-8-ol (148-24-3)
Molecular Formula C9H7NO C9H7NO (Isomeric)
Purity ≥98% (HPLC) ≥95%
Appearance Off-white crystalline powder Yellowish powder
Storage -20°C, protected from light Room temperature

2. Key Applications of Isoquinolin-6-ol

Isoquinolin-6-ol serves critical roles in:

  • Pharmaceuticals: Intermediate in antitumor drug synthesis (e.g., Camptothecin analogs).
  • Agrochemicals: Precursor for fungicide development.
  • Coordination Chemistry: Ligand for transition metal catalysts in asymmetric synthesis.
  • Material Science: Building block for organic semiconductors.

3. Usage Guidelines & Best Practices

  • Always use inert atmosphere (N2/Ar) during reactions to prevent oxidation.
  • Recommended solvent systems: DMF, THF, or dichloromethane.
  • Optimal reaction temperature range: 0°C to 40°C.
  • Storage: Reseal immediately after use; desiccate at -20°C.

4. Industry Use Cases

Industry Application Performance Metric
Oncology Research Synthesis of Topotecan intermediates Yield improvement: 72% → 89%
Catalysis Asymmetric hydrogenation of ketones ee: 95% (R)

5. Client Success Stories

Case 1: PharmaTech Innovations

Challenge: Low yield (68%) in kinase inhibitor synthesis.
Solution: Implemented Isoquinolin-6-ol as directing group.
Result: 92% yield; 99% purity.

Case 2: AgroSolutions Ltd.

Challenge: Degradation of fungicide intermediates.
Solution: Used Isoquinolin-6-ol as stabilizer.
Result: Shelf-life extended from 3 to 18 months.

6. Request a Quote or Technical Support

Contact our experts for bulk pricing, SDS, or synthetic pathway optimization:

Response time: <1 business day. Custom synthesis available.

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