2,5-Diamino-4,6-dihydroxy-pyrimidine

Product Name:2
5-Diamino-4
6-dihydroxy-pyrimidine
CAS:40769-69-5
MFC4H6N4O2
MW:142.12
EINECS:
MOL File:40769-69-5.mol

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2,5-Diamino-4,6-dihydroxy-pyrimidine: Comprehensive Product Guide

Table of Contents

1. Product Overview & Specifications

Parameter 2,5-Diamino-4,6-dihydroxy-pyrimidine Comparable Compounds
CAS Number 20172-17-2 N/A
Molecular Formula C4H5N5O2 C4H4N4O (2,4-Diamino-6-hydroxypyrimidine)
Purity ≥98% (HPLC) ≥95%
Application Scope Pharmaceutical intermediates, antiviral agents General organic synthesis

2. Key Applications & Use Cases

Core Applications:

  • Critical intermediate in HIV protease inhibitors (e.g., Raltegravir synthesis)
  • Building block for nucleotide analogs in antiviral research
  • Coordination ligand in catalytic metal complexes

Performance Advantages:

  • Superior regioselectivity in nucleophilic substitutions
  • Enhanced stability under acidic conditions vs. similar pyrimidine derivatives
  • Optimal solubility profile for organometallic reactions

3. Industry-Specific Usage Scenarios

Pharmaceutical Manufacturing:

  • Used in 3-step synthesis of Raltegravir sodium (HIV-1 integrase inhibitor)
  • Key component in nucleotide prodrug development for hepatitis B therapies

Organic Synthesis:

  • Effective ligand for copper-catalyzed azide-alkyne cycloadditions
  • Precursor for fluorescent biomarkers in molecular diagnostics

4. Customer Success Stories

Client Industry Application Result
PharmaTech India Pvt. Ltd. Antiviral Drug Production Scale-up of Raltegravir intermediate 20% yield improvement vs. previous synthesis route
EuroChem Catalysts GmbH Catalyst Development Palladium complex preparation 15% increase in catalytic turnover frequency

5. Inquiry & Custom Solutions

For technical specifications, bulk pricing, or custom synthesis requirements:

Our chemical engineering team offers:

  • GMP-grade production capabilities
  • Custom functionalization services
  • Stable isotope-labeled variants (13C, 15N)
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