2-Amino-3-bromo-5-methylpyridine

Product Name:2-Amino-3-bromo-5-methylpyridine
CAS:17282-00-7
MFC6H7BrN2
MW:187.04
EINECS:626-356-2
MOL File:17282-00-7.mol

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2-Amino-3-bromo-5-methylpyridine: Comprehensive User Guide

Table of Contents

1. Product Overview & Specifications

Parameter Specification
CAS Number NA
Molecular Formula C6H6BrN2
Molecular Weight 186.03 g/mol
Appearance White to off-white crystalline powder
Purity (HPLC) >98%
Storage Conditions 2-8°C in airtight container

2. Key Applications & Industrial Uses

Pharmaceutical Intermediate

Critical building block for:

  • Kinase inhibitor development
  • Anticancer drug candidates
  • Neurological disorder treatments

Agrochemical Synthesis

Essential component in:

  • Next-generation pesticides
  • Herbicide formulations
  • Fungicide active ingredients

3. Usage Guidelines & Best Practices

Handling Procedures

  • Use nitrogen atmosphere for sensitive reactions
  • Maintain pH 6-8 in aqueous solutions

Reaction Optimization

Reaction Type Optimal Conditions
Buchwald-Hartwig Amination Pd(dba)2, Xantphos, 110°C
Suzuki Coupling Pd(PPh3)4, K2CO3, 80°C

4. Comparative Analysis

Compound Reactivity Cost Efficiency
2-Amino-3-bromo-5-methylpyridine High $$$
2-Bromo-5-methylpyridine Medium $$

5. Real-World Case Studies

Case 1: Oncology Drug Development

Client: Top 10 Pharma Company

  • Application: PARP inhibitor intermediate
  • Result: 40% yield improvement

Case 2: Crop Protection Formulation

Client: Global Agrochemical Producer

  • Application: Systemic insecticide
  • Result: EPA approval in 12 months

6. Procurement Strategy

Quality Parameters

  • Require batch-specific COA
  • GC-MS impurity profile analysis

7. Technical Support & Contact

For custom synthesis or bulk quotes:

  • Email: info@vivalr.com
  • Phone: (86) 15866781826
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