BOC-Piperazine: Comprehensive User Guide for Researchers & Industry Professionals
Table of Contents
1. Product Overview & Technical Specifications
BOC-Piperazine (CAS 101385-93-7) is a premium-grade chemical intermediate specifically engineered for:
| Parameter | Specification | Competitor A | Competitor B |
|---|---|---|---|
| Purity | ≥99.5% | 98.7% | 97.9% |
| Molecular Weight | 214.26 g/mol | 214.26 g/mol | 214.26 g/mol |
| Storage Temperature | 2-8°C | Ambient | Ambient |
| Shelf Life | 36 months | 24 months | 18 months |
Key differentiators:
- Superior thermal stability (up to 150°C)
- NMR purity verification with each batch
- Customizable particle size (50-200μm available)
2. Key Applications & Industrial Uses
BOC-Piperazine serves critical functions in:
Pharmaceutical Synthesis
- Anticancer drug intermediates
- HIV protease inhibitors
- Neurological disorder treatments
Advanced Material Science
- Polymer cross-linking agents
- Epoxy resin modifiers
- Coating additives
3. Operational Best Practices
Recommended Workflow:
- Pre-cool reaction vessel to -20°C
- Use anhydrous DCM as primary solvent
- Maintain pH between 6.8-7.2
- Gradual temperature ramping (2°C/min)
Safety Protocols:
| Parameter | Requirement |
|---|---|
| PPE | Class III chemical gloves |
| Ventilation | ≥10 ACH |
| Spill Management | Neutralize with 5% citric acid |
4. Implementation Case Studies
Case 1: Oncology Drug Development
Challenge: Achieve 99% enantiomeric excess in kinase inhibitor synthesis
Solution: BOC-Piperazine-mediated stereochemical control
Outcome: 99.2% ee achieved with 15% yield improvement
Case 2: High-Performance Coatings
Challenge: Improve polymer Tg without viscosity increase
Solution: 2.5% BOC-Piperazine additive
Outcome: Tg increased from 85°C to 112°C
5. Client Success Stories
| Client | Industry | Results Achieved |
|---|---|---|
| Shanghai PharmaTech | Pharmaceuticals | Reduced synthesis steps from 7 to 4 in PARP inhibitor production |
| Guangdong Materials Co. | Chemical Manufacturing | 40% reduction in side reactions during scale-up |
| National University of Singapore | Academic Research | Enabled novel carborane-piperazine hybrid synthesis |
6. Technical Support & Inquiry
Our chemical engineering team provides:
- Free technical consultation
- Custom synthesis protocols
- Regulatory compliance support
Contact our specialists:
Email: info@vivalr.com
Phone: (86) 15866781826


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