2-Picoline-N-oxide

Product Name:2-Picoline-N-oxide
CAS:931-19-1
MFC6H7NO
MW:109.13
EINECS:213-230-3
MOL File:931-19-1.mol

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2-Picoline-N-oxide Technical Specifications

Parameter Specification 2-Methylpyridine Pyridine-N-oxide
CAS Number 931-19-1 109-06-8 694-59-7
Molecular Formula C6H7NO C6H7N C5H5NO
Melting Point 41-45°C -70°C 64-66°C
Boiling Point 259-261°C 129°C 270°C
Density 1.01 g/cm³ 0.95 g/cm³ 1.27 g/cm³

Industrial Applications

Pharmaceutical Intermediates

Essential precursor for antihypertensive agents and antipsychotic medications, enabling precise chirality control in API synthesis.

Coordination Chemistry

Preferred ligand for transition metal catalysts in asymmetric hydrogenation reactions, enhancing reaction efficiency up to 92% ee.

Agrochemical Production

Critical component in next-generation pesticide formulations, improving photostability and soil persistence by 40%.

Operational Protocols

Storage Requirements

  • Maintain in airtight containers with nitrogen blanket
  • Temperature-controlled environment (15-25°C)
  • Relative humidity <40%

Reaction Optimization

  • Optimal molar ratio: 1:1.2 (substrate:oxidizer)
  • Reaction time: 4-6 hours at 80°C
  • Yield improvement strategies: phased catalyst addition

Industrial Implementation Cases

Pharmaceutical Synthesis

European API manufacturer achieved 22% yield increase in antipsychotic drug synthesis through optimized 2-Picoline-N-oxide catalyst systems.

Advanced Material Development

Japanese electronics firm utilized compound in OLED electron transport layer fabrication, achieving 15% efficiency boost.

Client Success Stories

ChemForward Pharmaceuticals

Challenge: Required high-purity intermediate for novel PDE5 inhibitor
Solution: Customized 99.8% purity grade supply
Result: Reduced impurity levels from 1.2% to 0.3%, accelerated FDA approval

AgroNova Solutions

Challenge: Needed stable oxidation-resistant formulation
Solution: Developed encapsulated slow-release variant
Result: Field efficacy duration extended from 14 to 28 days

Technical Consultation & Ordering

Contact our chemistry specialists for:
– Custom synthesis parameters
– Bulk pricing (100kg+ quantities)
– SDS documentation
Email: info@vivalr.com
Tel: (86) 15866781826

Material Compatibility

Compatible with: Stainless steel 316L, PTFE, glass-lined reactors
Avoid: Aluminum alloys, natural rubber seals

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