3-Bromopyridin-4-ylboronic Acid: Comprehensive Product Guide
Table of Contents
- Product Overview & Specifications
- Key Applications & Industrial Uses
- Performance Comparison with Alternatives
- Usage Guidelines & Best Practices
- Industry Case Studies
- Request Customized Solutions
1. Technical Specifications
Basic Parameters
| Parameter | Specification |
|---|---|
| CAS Number | 1072951-79-6 |
| Molecular Formula | C5H4BBrNO2 |
| Purity | ≥97% (HPLC) |
| Storage Conditions | 2-8°C in inert atmosphere |
Comparative Analysis
| Feature | 3-Bromopyridin-4-ylboronic Acid | Similar Boronates |
|---|---|---|
| Reactivity in Coupling | High (kobs = 0.45 min-1) | Moderate (0.22-0.35 min-1) |
| Thermal Stability | Stable up to 150°C | Degrades above 120°C |
2. Industrial Applications
Pharmaceutical Synthesis
Critical intermediate for kinase inhibitors (JAK/STAT pathway modulators) with demonstrated efficacy in:
- Oncology therapeutics
- Autoimmune disease treatments
- Neurological disorder R&D
Material Science
Enables development of advanced functional materials:
- OLED charge transport layers
- Coordination polymers for catalysis
3. Operational Protocols
Suzuki-Miyaura Coupling
Optimal reaction conditions:
| Parameter | Value |
|---|---|
| Catalyst | Pd(PPh3)4 (2 mol%) |
| Base | Na2CO3 (3 equiv) |
4. Client Success Stories
Case 1: Top 10 Pharma Company
Challenge: Required scalable synthesis of BTK inhibitor intermediate
Solution: Optimized coupling yield from 68% to 92% using our product
Outcome: Reduced production costs by 40%
Case 2: Electronic Materials Startup
Challenge: Needed stable boronate for OLED development
Solution: Provided custom purification protocol
Outcome: Achieved 18% EQE in prototype devices
5. Technical Support & Ordering
Custom Synthesis Options
Available modifications:
- Isotope-labeled versions (13C, 15N)
- Bulk quantities (100kg+ batches)
Contact Our Experts
Email: info@vivalr.com
Phone: (86) 15866781826
Request:
- MSDS Documentation
- Stability Data
- Custom Synthesis Quotes
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