1. Product Overview & Specifications

Chemical Profile

IUPAC Name: 3”-Amino-2”-Hydroxy-Biphenyl-3-Carboxylic Acid
CAS Number: 1218790-34-2
Molecular Formula: C₁₃H₁₁NO₃
Molecular Weight: 229.23 g/mol
Appearance: Off-white to pale yellow crystalline powder
Purity: ≥98% (HPLC)
Solubility: Soluble in DMSO, methanol; sparingly soluble in water.

Competitive Comparison

2. Key Applications & Use Cases

Pharmaceutical Intermediates

Critical building block for kinase inhibitors and non-steroidal anti-inflammatory drugs (NSAIDs). The amino and hydroxyl groups enable selective functionalization for targeted drug design.

Material Science

Used in synthesis of:
– Metal-organic frameworks (MOFs)
– Conductive polymers
– Fluorescent sensors

Organic Synthesis

Acts as:
– Chelating ligand in transition metal catalysis
– Precursor for chiral auxiliaries
– Photoacid generator (PAG) in lithography

3. Industry Applications

Case Study A: Anti-Cancer Drug Development

Reaction: Suzuki-Miyaura coupling with bromopyridine
Yield: 82% (vs. 68% with similar compounds)
Application: EGFR inhibitor intermediate for lung cancer therapy

Case Study B: MOF Synthesis

Process: Coordinated with Zn(II) ions
Surface Area: 1,450 m²/g (BET)
Use: CO₂ capture in industrial emissions

4. Client Success Stories

PharmaGen Solutions (USA)

Challenge: Needed high-purity intermediate for Phase II clinical trial compound
Result: Achieved 99.2% purity via recrystallization, accelerating FDA submission by 3 months.

UniChem Research Institute (Germany)

Project: Development of fluorescence-based pH sensors
Outcome: Created sensor with 92% quantum yield using carboxyl group coordination.

NanoMaterials Co., Ltd (China)

Objective: Improve MOF thermal stability
Solution: Structural reinforcement through biphenyl backbone, achieving 400°C stability.

5. Technical Support & Inquiry

Our chemists provide:
– Custom synthesis scaling (mg to kg)
– HPLC/HNMR validation reports
– Regulatory support (REACH, TSCA)

Contact Our Experts:
Email: info@vivalr.com
Tel: (86) 15866781826