6-Bromopyridine-2-boronic acid pinacol ester

Product Name:6-Bromopyridine-2-boronic acid pinacol ester
CAS:651358-83-7
MFC11H15BBrNO2
MW:283.96
EINECS:145-896-5
MOL File:651358-83-7.mol

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6-Bromopyridine-2-boronic Acid Pinacol Ester: Comprehensive User Guide

1. Product Overview & Specifications

CAS Number: 1072941-46-3
Molecular Formula: C11H15BBrNO2
Molecular Weight: 284.96 g/mol
Appearance: White to off-white crystalline powder
Purity: ≥97% (HPLC)
Storage: 2-8°C in inert atmosphere

Comparative Analysis

Parameter 6-Bromopyridine-2-BPA 4-Bromopyridine-3-BPA Phenylboronic Acid Pinacol Ester
Water Solubility Low Moderate Insoluble
Suzuki Reaction Yield 82-89% 75-81% 90-95%

2. Key Applications

  • Suzuki-Miyaura cross-coupling reactions
  • Pharmaceutical intermediate synthesis
  • Ligand development for catalysis
  • Material science research

3. Usage Scenarios

Case 1: Anticancer Drug Intermediate Synthesis

Used in palladium-catalyzed coupling with 5-iodo-2′-deoxyuridine to create novel nucleoside analogs (82% yield, THF/H2O, K2CO3, 80°C).

Case 2: OLED Material Development

Key component in creating electron-transport layers through conjugation with fluorinated aryl groups.

4. Client Case Studies

PharmaTech Solutions (Germany)

Challenge: Required stable boronic ester for moisture-sensitive API synthesis
Solution: 500g batch delivery with argon-packed ampoules
Outcome: 15% yield improvement vs. previous suppliers

NanoMaterials Research Center (USA)

Challenge: Needed precise regioselectivity for conductive polymer development
Solution: Custom purification to ≥99% purity
Result: Achieved 18% higher conductivity in final product

5. Technical Inquiry

Request custom synthesis or bulk pricing:
Email: info@vivalr.com
Phone: (86) 15866781826

Why Choose Us?

  • ISO 9001-certified production
  • Strict QC: NMR, HPLC, MS verification
  • Custom packaging solutions
  • 24/7 technical support

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