4,6-Dimethyl-2-hydroxypyrimidine: Comprehensive Product Guide
Table of Contents
1. Product Overview & Specifications
4,6-Dimethyl-2-hydroxypyrimidine (CAS 108-53-2) is a heterocyclic organic compound with the molecular formula C6H8N2O. Key parameters:
| Parameter | Value |
|---|---|
| Molecular Weight | 124.14 g/mol |
| Appearance | White to off-white crystalline powder |
| Purity | ≥99% (HPLC) |
| Melting Point | 215-218°C |
| Solubility | Soluble in DMSO, methanol; sparingly in water |
Comparative Analysis
| Compound | Melting Point | Bioactivity | Cost Efficiency |
|---|---|---|---|
| 4,6-Dimethyl-2-hydroxypyrimidine | 215-218°C | High | $$$ |
| 2-Hydroxypyrimidine | 180-183°C | Medium | $$ |
2. Key Applications & Uses
- Pharmaceutical Intermediates: Core building block for antiviral/anticancer drugs
- Organic Synthesis: Ligand in transition metal catalysis
- Agrochemicals: Precursor for fungicides and herbicides
- Research: Study of nucleic acid analogs and enzyme inhibitors
3. Usage Guidelines
- Store at 2-8°C in airtight containers
- Use PPE during handling (gloves, goggles)
- Optimal reaction concentration: 0.1-0.5M in polar aprotic solvents
4. Application Case Studies
Case 1: Antiviral Drug Development
Used as key intermediate in remdesivir analog synthesis (yield improvement: 22%)
Case 2: Polymer Catalysis
Enhanced reaction rate by 40% in polyurethane production vs. traditional catalysts
5. Client Success Stories
ABC Pharmaceuticals
Challenge: Low yield in kinase inhibitor synthesis
Solution: Optimized coupling reactions using 4,6-dimethyl-2-hydroxypyrimidine
Result: 35% yield increase, reduced side products
XYZ AgroChem
Developed novel fungicide formulation with 98% pathogen inhibition rate
6. Request Custom Formulations
Contact our chemists for bulk orders or derivative synthesis:
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