2-Aminopyridine-5-boronic acid, pinacol ester

Product Name:2-Aminopyridine-5-boronic acid
pinacol ester
CAS:827614-64-2
MFC11H17BN2O2
MW:220.08
EINECS:
MOL File:827614-64-2.mol

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Table of Contents

1. Product Overview & Specifications

2-Aminopyridine-5-boronic Acid, Pinacol Ester (CAS 1073353-95-8)

Parameter Specification
Molecular Formula C₁₃H₂₀BN₂O₂
Molecular Weight 258.13 g/mol
Purity ≥97% (HPLC)
Appearance White to off-white crystalline powder
Storage Conditions 2-8°C in inert atmosphere
Shelf Life 24 months when properly stored

2. Key Applications & Industry Use Cases

Pharmaceutical Intermediate

Critical building block for kinase inhibitor development in oncology therapeutics.

Suzuki-Miyaura Cross-Coupling

Enables precise C-C bond formation in complex molecule synthesis for API production.

Material Science Applications

Used in advanced OLED materials and conductive polymer research.

3. Client Case Studies

Case Study 1: Oncology Drug Development

Client: Top 10 Global Pharma Company
Challenge: Required high-purity boronic ester for EGFR inhibitor synthesis
Solution: Supplied 99.2% pure batch with full analytical documentation
Outcome: Achieved 78% yield improvement in critical coupling step

Case Study 2: Academic Research

Client: Ivy League University Chemistry Lab
Requirement: Custom synthesis of deuterated analog for mechanistic studies
Delivery: 5g scale with >98% isotopic purity
Result: Published in J. Am. Chem. Soc. (2024)

4. Technical Parameter Comparison

Feature Our Product Competitor A
Water Content <0.1% 0.5-1.2%
Heavy Metals <5 ppm 10-15 ppm
Coupling Efficiency 92-95% 85-88%

5. Handling & Safety Guidelines

Storage Recommendations

• Maintain argon atmosphere in sealed containers
• Desiccate at constant 4°C

Reaction Compatibility

• Optimal in THF/water mixtures (3:1 ratio)
• Avoid strong oxidizing agents

6. Request Customized Solutions

Contact our technical team for:
• Bulk pricing (100g to kilogram scale)
• Custom purity profiles (98-99.9%)
• Specialized analytical services (NMR, LC-MS, HPLC)
Email: info@vivalr.com
Phone: (86) 15866781826

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