5-Hydroxypyrazine-2-carboxylic Acid: Comprehensive User Guide
Table of Contents
1. Product Overview & Comparative Analysis
Chemical Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 1005-24-9 |
| Molecular Formula | C5H4N2O3 |
| Molecular Weight | 140.10 g/mol |
| Appearance | White to off-white crystalline powder |
| Purity (HPLC) | ≥98% |
| Solubility | Soluble in DMSO, methanol; sparingly in water |
| Storage | 2-8°C in airtight container |
Competitor Comparison
| Vendor | Purity | Price/kg | Lead Time |
|---|---|---|---|
| Vivalr Chemical | ≥98% | $850 | 2-3 weeks |
| Supplier A | ≥95% | $920 | 4-5 weeks |
| Supplier B | ≥97% | $890 | 3-4 weeks |
2. Key Applications & Industrial Uses
Pharmaceutical Intermediates
Essential precursor for:
- Antitubercular agents (e.g., Pretomanid derivatives)
- Kinase inhibitor synthesis
- Anticancer drug candidates
Chemical Research
- Ligand development for metal-organic frameworks
- Building block for heterocyclic compounds
3. Operational Best Practices
Handling Protocols
- Use PPE: Nitrile gloves, safety goggles
- Work in fume hood for bulk quantities
Reaction Optimization
| Reaction Type | Optimal Conditions | Yield |
|---|---|---|
| Amidation | DCM, 0-5°C, 24h | 82-85% |
| Esterification | SOCl2 catalyst, reflux | 78-80% |
4. Implementation Case Studies
Case 1: Antiviral Drug Development
Challenge: Improve yield in nucleoside analog synthesis
Solution: Used as coupling agent at 0.5 molar ratio
Outcome: 22% yield increase vs. traditional methods
5. Client Success Stories
PharmaTech Solutions (Germany)
“Vivalr’s 5-Hydroxypyrazine-2-carboxylic acid enabled 15% cost reduction in our API manufacturing process through improved reaction efficiency.”
BioSynthetics Co., Ltd (USA)
“Consistent ≥98% purity met our strict QC requirements for GLP-compliant preclinical studies.”
6. Technical Consultation & Quotation
Contact our chemical experts for:
- Custom synthesis options
- Bulk pricing (100kg+ orders)
- Technical documentation support
Email: info@vivalr.com
Phone: (86) 15866781826
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