Quinoline-7-carbaldehyde: Comprehensive Product Guide
Table of Contents
1. Product Overview & Specifications
Quinoline-7-carbaldehyde (CAS: 49573-30-0) is a high-purity organic compound with the molecular formula C10H7NO and a molecular weight of 157.17 g/mol. Also known as 7-Quinolinecarboxaldehyde, it is widely utilized in pharmaceutical intermediates and material science research.
Key Parameters:
Property | Value |
---|---|
Melting Point | 87°C |
Boiling Point | 314.3°C at 760 mmHg |
Density | 1.223 g/cm³ |
Refractive Index | 1.687 |
Purity | ≥97% (GC) |
2. Key Applications & Use Cases
- Pharmaceutical Synthesis: Serves as a critical intermediate in the production of antimicrobial agents and kinase inhibitors.
- Material Science: Used to develop luminescent materials and metal-organic frameworks (MOFs).
- Agrochemicals: Functions as a precursor for crop protection agents targeting bacterial pathogens.
3. Technical Comparison with Derivatives
Compound | CAS | Molecular Formula | Key Difference |
---|---|---|---|
3-Bromoquinoline-7-carbaldehyde | 1259224-17-3 | C10H6BrNO | Enhanced reactivity for cross-coupling reactions |
Quinoline-6-carbaldehyde | 4113-04-6 | C10H7NO | Altered regioselectivity in substitution reactions |
4. Client Case Studies
Case 1: Shanghai Yuanye Bio-Tech Co., Ltd.
Application: Synthesis of a novel anticancer drug candidate. Quinoline-7-carbaldehyde was used to develop a selective kinase inhibitor, achieving 95% yield in palladium-catalyzed coupling reactions.
Case 2: Beijing Solarbio Science & Technology Co., Ltd.
Application: Production of corrosion-resistant coatings. The compound’s aldehyde group enabled covalent bonding with polymer matrices, improving material stability by 40% under acidic conditions.
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