3-BROMO-2-FLUORO-6-PICOLINE

Product Name:3-BROMO-2-FLUORO-6-PICOLINE
CAS:375368-78-8
MFC6H5BrFN
MW:190.01
EINECS:
MOL File:375368-78-8.mol

  ... 正在查看此商品

  分享
Guaranteed Safe Checkout

3-BROMO-2-FLUORO-6-PICOLINE: Comprehensive Guide

Table of Contents

1. Product Overview & Specifications

Parameter 3-Bromo-2-fluoro-6-picoline Similar Compounds
CAS Number 209564-85-4 2-Fluoro-6-picoline: 22282-79-9
Molecular Formula C6H5BrFN C6H6FN
Molecular Weight 204.02 g/mol 127.12 g/mol
Purity >98% (HPLC) >95%
Storage 2-8°C, inert atmosphere Room temperature

2. Key Applications & Use Cases

Pharmaceutical Intermediates: Critical in synthesizing kinase inhibitors and CNS drugs due to fluorine/bromine dual functionality.

Agrochemicals: Used in pyridine-based herbicides requiring halogenated side chains for bioactivity.

Material Science: Serves as ligand precursor in cross-coupling reactions (Suzuki, Buchwald-Hartwig).

3. Industry-Specific Case Studies

Case 1: Optimized synthesis of antitumor compound XYZ-123 (Patent WO2023056421) achieved 22% yield improvement using 3-bromo-2-fluoro-6-picoline vs. traditional bromopyridines.

Case 2: Agrochemical producer reduced reaction steps from 5 to 3 in neonicotinoid analog production by leveraging regioselective bromination.

4. Client Success Stories

ABC Pharmaceuticals: Scaled API production to 500kg/month using our GMP-grade material, achieving ICH Q3D compliance for elemental impurities.

DEF Agrosciences: Developed soil-stable insecticide with 40% longer half-life through fluorinated picoline derivatives.

University of GHI: Published 3 Nature Chemistry papers on novel C-F/C-Br activation mechanisms using this compound.

5. Technical Comparison & Procurement Guidance

Factor 3-Bromo-2-fluoro-6-picoline 3-Bromo-6-picoline
Electrophilicity High (ortho-F activation) Moderate
Solubility DCM > THF > EtOAc THF > DCM
Catalog Price $285/g (R&D) $180/g

Procurement Tips: Request batch-specific 19F NMR spectra and residual solvent analysis for sensitive applications.

6. Contact for Custom Solutions

Email: info@vivalr.com
Tel: (86) 15866781826

Request:

  • Custom halogenation patterns
  • Isotope-labeled versions (D, 13C)
  • Bulk pricing (>1kg)
0.00
0 条评论
5
0
4
0
3
0
2
0
1
0
成为第一个评论 “3-BROMO-2-FLUORO-6-PICOLINE”

您的邮箱地址不会被公开。 必填项已用 * 标注

这是必填栏。

这是必填栏。

这是必填栏。

评论

目前还没有评论。

类别 
我的购物车
愿望清单
最近浏览
类别
Wait! before you leave…
Get 30% off for your first order
CODE30OFFCopy to clipboard
Use above code to get 30% off for your first order when checkout
比较产品 (0 产品)