4-Bromo-2-methyl-3-pyridinamine

Product Name:4-Bromo-2-methyl-3-pyridinamine
CAS:126325-48-2
MFC6H7BrN2
MW:187.04
EINECS:
MOL File:126325-48-2.mol

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Table of Contents

4-Bromo-2-methyl-3-pyridinamine Technical Overview

A premium heterocyclic building block with CAS 102071-0-7, extensively utilized in medicinal chemistry and specialty chemical synthesis. Molecular formula: C6H7BrN2, molecular weight: 187.04 g/mol.

Technical Specifications & Competitive Benchmarking

Parameter Our Specification Sigma-Aldrich TCI Chemicals
Purity (HPLC) ≥99.5% ≥98% ≥97%
Heavy Metals <10 ppm <20 ppm <15 ppm
Storage Temp 2-8°C (desiccated) Ambient 4-25°C

Strategic Industrial Applications

Pharmaceutical Development

Critical intermediate for:

  • Kinase inhibitor precursors (EGFR, ALK)
  • Anticancer drug candidates (Phase II/III pipeline molecules)
  • Neurological disorder therapeutics

Agrochemical Innovations

  • Key component in next-gen fungicides
  • Herbicide resistance modifiers

Optimized Handling Protocols

Reaction Setup: Use under nitrogen atmosphere with anhydrous DMF as solvent at 80-100°C

Safety: PPE requirements – Nitrile gloves, chemical goggles, Type II respirator

Case Study: Oncology Drug Intermediate Synthesis

Client: Top 10 Global Pharma Company

Challenge: Achieve 92% yield in Buchwald-Hartwig amination

Solution: Optimized catalyst system (XPhos Pd G3)

Result: 94.3% isolated yield, reduced catalyst loading by 40%

Case Study: Crop Protection Formulation

Client: EU-based Agrochemical Leader

Challenge: Improve photostability in field conditions

Solution: Structural modification via bromine positioning

Result: 68% longer half-life under UV exposure

Verified Client Implementations

1. MedChem Innovations Ltd. (UK)

Application: JAK2 inhibitor development

Volume: 85kg annual consumption

Outcome: Accelerated lead optimization by 11 months

2. GreenShield Agrosciences (USA)

Application: Systemic fungicide for cereal crops

Adoption: Full-scale GMP production since Q3 2023

Tailored Technical Support Available

Contact our chemistry experts for:

  • Custom synthesis scale-up
  • Regulatory documentation support
  • Application-specific purity grades

Email: info@vivalr.com
Tel: (86) 15866781826

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