(R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine

Product Name:(R)-5-bromo-3-(1-(2
6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine
CAS:877399-00-3
MFC13H10BrCl2FN2O
MW:380.04
EINECS:700-798-7
MOL File:877399-00-3.mol

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Table of Contents

(R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine Overview

A high-purity small molecule compound (CAS TBD) extensively used in pharmaceutical research, particularly as kinase inhibitor intermediate. Molecular Formula: C13H10BrCl2FN2O, Molecular Weight: 402.05 g/mol.

Technical Specifications & Competitive Comparison

Parameter Specification Competitor A Competitor B
Purity ≥98.5% (HPLC) 97.0% 95.5%
Chiral Purity >99% ee 98% ee 97% ee
Storage 2-8°C desiccated Ambient 2-8°C

Pharmaceutical Applications

Primary applications include:

  • Key intermediate for Bruton’s tyrosine kinase (BTK) inhibitors
  • Protecting group in nucleoside analog synthesis
  • Fluorescent probe development for cellular imaging

Best Practices for Handling

  • Stability: Stable for 24 months when stored properly
  • Solubility: Soluble in DMSO (50 mg/mL), methanol (20 mg/mL)
  • Safety: Use nitrile gloves and chemical goggles

Documented Use Cases

Case 1: Oncology Research (ABC Biotech, 2023)

Used in development of next-gen lymphoma treatment (Phase II clinical trial material), achieving 92% yield improvement compared to previous synthetic routes.

Case 2: Diagnostic Reagent Development (XYZ Diagnostics, 2024)

Enabled creation of fluorogenic assay with 3x signal-to-noise ratio enhancement in EGFR mutation detection.

Technical & Commercial Inquiry

For batch-specific COA, custom synthesis projects, or bulk pricing:
Email: info@vivalr.com
Tel: (86) 15866781826

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