tert-Butyl 6-(5-(7-Bromo-9,9-difluoro-9H-fluoren-2-yl)imidazol-2-yl)-5-azaspiro[2.4]heptane-5-carboxylate: Technical Guide & Applications
Table of Contents
1. Product Overview & Specifications
| Parameter | Specification | Competitor A | Competitor B |
|---|---|---|---|
| CAS Number | 1441670-89-8 | N/A | 24424-99-5 |
| Molecular Formula | C30H31BrF2N3O2 | C10H18O5 | C14H18BrNO2 |
| Molecular Weight | 608.49 g/mol | 218.25 g/mol | 312.2 g/mol |
| Storage Conditions | 2-8°C in inert atmosphere | Ambient | -20°C |
2. Key Applications & Functional Properties
This advanced intermediate is critical for:
- Pharmaceutical synthesis (kinase inhibitors, antiviral agents)
- OLED material development via fluorene derivatives
- Cross-coupling reactions enabled by bromo functionality
- Spirocyclic compound research for drug bioavailability
3. Operational Guidelines
Handling Protocols:
- Use dry argon glovebox for weighing
- Maintain reaction temperatures below 80°C
- Quench with ice-cold methanol post-reaction
4. Industry Case Studies
Case 1: SolarBio Pharmaceuticals
Used in synthesizing novel EGFR inhibitors (78% yield improvement vs. traditional routes).
Case 2: Jiangsu Beida PharmaTech
Key intermediate for fluorene-based OLED emitters (CIE coordinates: 0.67, 0.33).
5. Inquiry & Technical Support
For batch-specific COA or custom synthesis:
Email: info@vivalr.com
Tel: (86) 15866781826
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