5-CHLOROTHIOPHENE-2-CARBONYL CHLORIDE: Ultimate Buyer’s Guide (2024)
Contents
- Product Overview & Specifications
- Key Applications & Industrial Uses
- Operational Best Practices
- Real-World Case Studies
- Procurement Strategies
- Connect with Experts
Technical Specifications & Comparative Analysis
| Parameter | 5-Chlorothiophene-2-carbonyl chloride | Thiophene-2-carbonyl chloride | 2-Chlorobenzoyl chloride |
|---|---|---|---|
| CAS Number | 40128-21-6 | 5271-68-1 | 609-65-4 |
| Molecular Formula | C5H2Cl2OS | C5H3ClOS | C7H4Cl2O |
| Reactivity | High (Thiophosgene analog) | Moderate | Moderate-High |
| Pharma Compatibility | API Intermediate Grade | Research Grade | Industrial Grade |
Industrial Applications Breakdown
Pharmaceutical Intermediates
Critical component in synthesis of:
- Antiviral agents (HCV/HIV protease inhibitors)
- Kinase inhibitors for oncology treatments
- Antipsychotic drug precursors
Agrochemical Synthesis
- Chlorinated neonicotinoid insecticides
- Fungicidal seed treatments
Handling & Storage Protocols
| Parameter | Requirement |
|---|---|
| Storage Temperature | 2-8°C under inert gas |
| Shelf Life | 12 months in original packaging |
| Reaction Quenching | Ethanol/ice bath recommended |
Verified Usage Scenarios
Case 1: Antiviral API Production (Jiangsu Alpharma, 2023)
- Challenge: Scale-up from lab to 500kg batches
- Solution: Optimized Schotten-Baumann conditions
- Outcome: 92% yield at commercial scale
Case 2: Next-Gen Insecticides (Syngenta Regional Facility)
- Developed moisture-resistant formulation
- Increased field persistence by 40%
Strategic Sourcing Advice
| Factor | Evaluation Criteria |
|---|---|
| Supplier Certification | Require DMF/CEP filings |
| Batch Traceability | HPLC chromatograms per batch |
Request Custom Quotes
Email: info@vivalr.com
Tel: (86) 15866781826
Specify requirements:
- Target purity (98%+/99%+)
- Packaging needs (ampoules/drums)
- Regulatory documentation
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