Pyridine-N-oxide: High-Purity Chemical Intermediate for Advanced Synthesis

CAS Number: 694-59-7 | Molecular Formula: C5H5NO | Purity: ≥99%

Technical Specifications & Competitive Analysis

Industrial Applications of Pyridine-N-oxide

Pharmaceutical Manufacturing

• Key intermediate in antiviral drug synthesis
• Catalyst in β-lactam antibiotic production

Organic Synthesis

• Oxidizing agent in Swern oxidations
• Ligand in transition metal catalysis

Operational Protocols

Pharmaceutical Intermediate Preparation

1. Charge reactor with 1.2 molar equivalents under N₂
2. Maintain temperature at -10°C to 5°C
3. Monitor reaction progress by TLC/HPLC

Documented Success Cases

Case 1: PharmaTech Solutions (2023)

Challenge: Low yield in remdesivir intermediate synthesis
Solution: Implemented our ≥99% grade as chiral auxiliary
Result: Yield increased from 68% → 89%

Case 2: ChemInnovate Inc. (2024)

Challenge: Catalyst deactivation in cross-couplings
Solution: Used as co-ligand with palladium
Result: Catalyst turnover number (TON) improved 12X

Technical Consultation & Sampling

Contact our chemists for:
– Custom purity specifications
– Bulk pricing (100kg+ orders)
– Regulatory documentation support

info@vivalr.com
(86) 15866781826

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