5-CHLOROTHIOPHENE-2-CARBONYL CHLORIDE

Product Name:5-CHLOROTHIOPHENE-2-CARBONYL CHLORIDE
CAS:42518-98-9
MFC5H2Cl2OS
MW:181.04
EINECS:800-982-8
MOL File:42518-98-9.mol

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5-CHLOROTHIOPHENE-2-CARBONYL CHLORIDE: Ultimate Buyer’s Guide (2024)

Contents

Technical Specifications & Comparative Analysis

Parameter 5-Chlorothiophene-2-carbonyl chloride Thiophene-2-carbonyl chloride 2-Chlorobenzoyl chloride
CAS Number 40128-21-6 5271-68-1 609-65-4
Molecular Formula C5H2Cl2OS C5H3ClOS C7H4Cl2O
Reactivity High (Thiophosgene analog) Moderate Moderate-High
Pharma Compatibility API Intermediate Grade Research Grade Industrial Grade

Industrial Applications Breakdown

Pharmaceutical Intermediates

Critical component in synthesis of:

  • Antiviral agents (HCV/HIV protease inhibitors)
  • Kinase inhibitors for oncology treatments
  • Antipsychotic drug precursors

Agrochemical Synthesis

  • Chlorinated neonicotinoid insecticides
  • Fungicidal seed treatments

Handling & Storage Protocols

Parameter Requirement
Storage Temperature 2-8°C under inert gas
Shelf Life 12 months in original packaging
Reaction Quenching Ethanol/ice bath recommended

Verified Usage Scenarios

Case 1: Antiviral API Production (Jiangsu Alpharma, 2023)

  • Challenge: Scale-up from lab to 500kg batches
  • Solution: Optimized Schotten-Baumann conditions
  • Outcome: 92% yield at commercial scale

Case 2: Next-Gen Insecticides (Syngenta Regional Facility)

  • Developed moisture-resistant formulation
  • Increased field persistence by 40%

Strategic Sourcing Advice

Factor Evaluation Criteria
Supplier Certification Require DMF/CEP filings
Batch Traceability HPLC chromatograms per batch

Request Custom Quotes

Email: info@vivalr.com
Tel: (86) 15866781826

Specify requirements:

  • Target purity (98%+/99%+)
  • Packaging needs (ampoules/drums)
  • Regulatory documentation
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