2-Amino-4,6-dihydroxypyrimidine

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2-Amino-4,6-dihydroxypyrimidine: Comprehensive User Guide

Table of Contents

1. Product Overview & Specifications

2-Amino-4,6-dihydroxypyrimidine (CAS 56-09-5) is a heterocyclic organic compound with molecular formula C4H5N3O2 and molecular weight 127.10 g/mol. This white to off-white crystalline powder shows water solubility up to 50 mg/mL at 20°C.

Parameter Specification
Purity ≥98% (HPLC)
Melting Point >300°C (dec.)
Storage 2-8°C in airtight container

2. Key Applications & Use Cases

Pharmaceutical Intermediate

Widely used in synthesizing antiviral agents and kinase inhibitors. Particularly effective in:

  • HIV protease inhibitor development
  • Anticancer drug candidate preparation
  • Tyrosine kinase inhibitor synthesis

Coordination Chemistry

Serves as polydentate ligand for transition metal complexes in:

  • Catalyst design for oxidation reactions
  • Metal-organic framework (MOF) construction
  • Electrochemical sensor development

3. Industry-Specific Case Studies

Case 1: Antiviral Drug Development

Challenge: Create nucleoside analogs with improved bioavailability
Solution: Used as base structure for prodrug modification
Result: 68% increase in oral absorption rate

Case 2: Sustainable Catalysis

Challenge: Develop reusable palladium-based catalyst
Solution: Created Pd(II)-pyrimidine complex
Result: Achieved 15 reaction cycles with <5% activity loss

4. Technical Parameter Comparison

Property 2-Amino-4,6-dihydroxypyrimidine Similar Compound A
Aqueous Solubility High (50 mg/mL) Low (8 mg/mL)
Thermal Stability >300°C 220°C
Pharma Compatibility Excellent Moderate

5. Client Success Stories

Client 1: European Pharma Company

Application: Hepatitis C treatment R&D
Usage: 15kg batch for lead optimization
Outcome: Reduced IC50 by 40% vs. previous candidates

Client 2: Asian Material Science Institute

Application: Conductive polymer additives
Usage: 8-month technical collaboration
Outcome: Developed material with 12 S/cm conductivity

6. Request Customized Solutions

Optimize your formulation with our technical expertise:

  • Custom purity grades (98-99.9%)
  • Bulk quantities (100kg+ production capacity)
  • GMP-compliant manufacturing

Contact our chemistry team:
Email: info@vivalr.com
Phone: (86) 15866781826

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