Table of Contents
- 1. Product Overview & Specifications
- 2. Key Applications of 2,6-Difluoropyridine
- 3. Usage Guidelines & Best Practices
- 4. Industry Case Studies
- 5. Client Success Stories
- 6. Request Customized Solutions
1. Product Overview & Specifications
1.1 Chemical Properties
2,6-Difluoropyridine (CAS 110553-19-4) is a fluorinated heterocyclic compound with molecular formula C5H3F2N. Key parameters:
| Parameter | Value |
|---|---|
| Purity | ≥99% (HPLC) |
| Melting Point | -14°C to -12°C |
| Boiling Point | 132-134°C |
| Density | 1.293 g/cm³ |
| Refractive Index | 1.443 |
1.2 Grade Comparison
| Grade | Pharmaceutical | Industrial | Research |
|---|---|---|---|
| Purity | ≥99.9% | ≥98% | ≥95% |
| Impurity Profile | ICH compliant | Standard | Basic |
| Packaging | Nitrogen-sealed | Vacuum-packed | Ambient |
2. Key Applications
2.1 Pharmaceutical Intermediates
Critical component in synthesizing:
- Kinase inhibitors (e.g., EGFR inhibitors)
- Antiviral agents
- PET radiopharmaceuticals
2.2 Agrochemical Formulations
Used in next-generation:
- Herbicides (Fluoropyridine-class)
- Insect growth regulators
3. Usage Guidelines
3.1 Handling Protocols
- Storage: -20°C under inert gas
- Shelf Life: 24 months unopened
3.2 Reaction Optimization
| Reaction Type | Catalyst | Yield Range |
|---|---|---|
| Suzuki Coupling | Pd(PPh3)4 | 78-85% |
| Buchwald-Hartwig | XPhos Pd G3 | 82-90% |
4. Industry Case Studies
4.1 Drug Development
Challenge: Improve solubility of oncology compound
Solution: 2,6-Difluoropyridine backbone modification
Result: 40% bioavailability increase
5. Client Success Stories
5.1 Top-tier Pharma Company (Confidential)
- Application: EGFR inhibitor development
- Volume: 150kg/year
- Outcome: Accelerated IND filing by 6 months
5.2 Agrochemical Leader
- Project: Herbicide resistance management
- Result: 92% weed control efficacy
6. Request Customized Solutions
Contact our technical team for:
- Bulk pricing (50kg+ orders)
- Custom fluorination services
- Regulatory support packages
Email: info@vivalr.com
Phone: (86) 15866781826
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