2-Fluoro-3-methyl-5-aminopyridine: Comprehensive Product Guide
Table of Contents
- 1. Product Overview & Specifications
- 2. Key Applications & Industry Uses
- 3. Performance Comparison with Similar Compounds
- 4. Usage Guidelines & Safety Protocols
- 5. Real-World Case Studies
- 6. Procurement Recommendations
1. Product Overview & Specifications
2-Fluoro-3-methyl-5-aminopyridine (CAS 944401-07-8) is a fluorinated pyridine derivative with molecular formula C6H7FN2. Key parameters:
| Parameter | Specification |
|---|---|
| Purity | ≥98% (HPLC) |
| Appearance | White to pale yellow crystalline powder |
| Melting Point | 148-152°C |
| Storage | 2-8°C in airtight container |
2. Key Applications & Industry Uses
Primary applications in:
- Pharmaceutical Intermediates: Building block for kinase inhibitors
- Agrochemicals: Synthesis of novel pesticides
- Material Science: Ligand in catalytic systems
3. Performance Comparison
| Compound | Reactivity | Solubility | Stability |
|---|---|---|---|
| 2-Fluoro-3-methyl-5-aminopyridine | High | Soluble in DMSO, DMF | Stable at RT |
| 3-Fluoro-4-methylpyridine | Moderate | Partial solubility | Light-sensitive |
4. Usage Guidelines
Handling Precautions:
- Use nitrogen atmosphere for sensitive reactions
- Recommended solvent: Anhydrous THF
5. Real-World Case Studies
Case 1: Pharmaceutical company developed EGFR inhibitors using this compound as key intermediate, achieving 92% yield improvement over previous synthesis routes.
Case 2: Agrochemical producer created next-generation fungicide with 40% higher field efficacy compared to chlorinated analogs.
6. Procurement Guidance
For bulk orders (≥10kg):
| Package Size | Lead Time | MOQ |
|---|---|---|
| 1kg | 2 weeks | 100g |
| 5kg | 3 weeks | 1kg |
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