Table of Contents
- Product Overview & Specifications
- Key Applications
- Usage Guidelines
- Industry Case Studies
- Request Customized Solutions
6-Bromopyridine-2-carbaldehyde: Product Overview & Specifications
Technical Parameters
| Parameter | Specification | Comparison with Pyridine Derivatives |
|---|---|---|
| CAS Number | 313546-41-7 | Unique halogenated structure |
| Molecular Formula | C₆H₄BrNO | Higher reactivity than non-brominated analogs |
| Purity | ≥98% (HPLC) | Superior to standard commercial grades |
| Melting Point | 72-75°C | Optimal for thermal-sensitive reactions |
Chemical Properties
6-Bromopyridine-2-carbaldehyde (MFCD11855703) features:
- Bromo group at 6-position enhances electrophilic substitution
- Formyl group enables nucleophilic additions
- Stable under inert atmosphere up to 150°C
Key Industrial Applications
Pharmaceutical Intermediates
Critical in synthesizing:
- Antiviral drug candidates (HCV protease inhibitors)
- Kinase inhibitor scaffolds
- Neurological disorder therapeutics
Organic Synthesis
- Suzuki-Miyaura coupling reactions
- Preparation of chiral ligands
- Metal-organic framework (MOF) construction
Optimal Usage Protocols
Handling Recommendations
| Condition | Requirement |
|---|---|
| Storage | 2-8°C under nitrogen |
| Solubility | DCM/THF > DMF > Ethanol |
| Reaction Compatibility | Compatible with Pd catalysts |
Synthetic Pathways
Typical reaction flow:
- Bromination of pyridine-2-carbaldehyde
- Pd-mediated cross-coupling reactions
- Purification via column chromatography
Industry Success Stories
Case Study 1: PharmaHealth Inc.
Challenge: Develop HCV NS5A inhibitor with >90% yield
Solution: Used 6-Bromopyridine-2-carbaldehyde as key building block
Result: Achieved 92% reaction efficiency, reduced production cost by 40%
Case Study 2: Advanced Material Solutions LLC
Challenge: Create luminescent MOFs for OLEDs
Solution: Incorporated bromopyridine derivative as linker
Result: Achieved 15% higher quantum yield vs traditional ligands
Request Customized Solutions
Our technical team provides:
- Bulk quantities (100g to 100kg)
- Custom purity profiles (98-99.9%)
- GMP-compliant manufacturing
Contact our specialists:
Email: info@vivalr.com
Phone: (86) 15866781826


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