4-Amino-2-chloro-5-methylpyrimidine

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4-Amino-2-chloro-5-methylpyrimidine: Comprehensive Product Guide

1. Product Overview & Specifications

4-Amino-2-chloro-5-methylpyrimidine (CAS 159793-52-5) is a high-purity chemical intermediate widely used in pharmaceutical and agrochemical research. Key parameters include:

Parameter Specification Competitor A Competitor B
Molecular Formula C5H6ClN3 C5H6ClN3 C5H6ClN3
Purity ≥98% ≥95% ≥97%
Melting Point 145-148°C 142-146°C 143-147°C
Solubility DMSO, Ethanol DMSO only Ethanol limited

2. Applications & Use Cases

Pharmaceutical Development

Acts as a critical intermediate in kinase inhibitors for oncology therapeutics.

Agrochemical Synthesis

Used in herbicides targeting broadleaf weed control with 30% faster action vs. traditional analogs.

3. Step-by-Step Usage Guidelines

  1. Storage: Keep at 2-8°C in airtight containers.
  2. Handling: Use nitrile gloves and fume hoods during synthesis.
  3. Reaction: Optimize at 80°C under nitrogen for 6 hours (yield: 89-92%).

4. Client Case Studies

Case 1: Top 10 Pharma Company

Challenge: Scale up a TLR7 inhibitor for autoimmune trials.
Solution: Used 4-Amino-2-chloro-5-methylpyrimidine in step 3 of 7-step synthesis.
Result: Achieved 85% overall yield (industry avg: 72%).

Case 2: EU Agrochemical Leader

Challenge: Develop low-toxicity herbicide for EU compliance.
Solution: Incorporated compound into novel pyrimidine-carbamate formula.
Result: Reduced environmental persistence by 40% vs. previous gen.

5. Request a Quote

Contact our technical team for bulk pricing, SDS, or custom synthesis:

info@vivalr.com
(86) 15866781826

Why Choose Us:
– ISO 9001-certified production
– 99.7% on-time delivery rate
– 24/7 technical support

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