2-Amino-5-hydroxypyrimidine

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2-Amino-5-hydroxypyrimidine Technical Guide

Table of Contents

1. Technical Specifications

Parameter Value
CAS Number 143489-45-6
Molecular Formula C4H5N3O
Molecular Weight 111.10 g/mol
Appearance White crystalline powder
Melting Point >170°C (decomposition)
Boiling Point 393.6°C at 760 mmHg
Storage Conditions 2-8°C in airtight container

2. Functional Applications

This heterocyclic compound serves as critical building block in:

  • Pharmaceutical intermediates for antiviral agents
  • Coordination chemistry for metal-organic frameworks
  • Nucleic acid analog synthesis
  • Agrochemical development
  • Advanced material science research

3. Industry Applications

3.1 Medicinal Chemistry

Used in development of kinase inhibitors targeting cancer pathways. The hydroxyl and amino groups enable hydrogen bonding with biological targets.

3.2 Organic Synthesis

Acts as precursor for synthesizing substituted pyrimidine derivatives through palladium-catalyzed cross-coupling reactions.

4. Client Implementations

Case Study 1: Pharma Research Lab

Challenge: Required high-purity precursor for HIV protease inhibitor development
Solution: Supplied 99.8% HPLC-grade material with full analytical documentation
Outcome: Accelerated lead compound optimization by 40%

Case Study 2: University Chemistry Dept

Challenge: Needed custom synthesis for coordination polymer study
Solution: Delivered 500g batch with modified particle size distribution
Outcome: Enabled successful publication in ACS Applied Materials

5. Procurement Considerations

  • Verify analytical certificates (HPLC, NMR, MS)
  • Confirm stability under intended storage conditions
  • Request regulatory documentation (REACH, TSCA)
  • Evaluate supplier QA/QC protocols

Contact our technical team for customized solutions:
Email: info@vivalr.com
Tel: (86) 15866781826

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