Parameter | Specification |
---|---|
CAS Number | 135058-86-5 |
Molecular Formula | C5H3BrClN |
Molecular Weight | 192.44 g/mol |
Purity | ≥98% (HPLC) |
Appearance | White to off-white crystalline powder |
Storage Conditions | 2-8°C in inert atmosphere |
Widely used in Suzuki-Miyaura cross-coupling reactions for kinase inhibitor synthesis.
Key precursor for chloronicotinoid insecticides with enhanced bioactivity.
Building block for conductive polymers in OLED manufacturing.
Typical reaction conditions: 80-100°C under N2 with Pd(PPh3)4 catalyst.
Requires handling in certified fume hoods with PPE including nitrile gloves and safety goggles.
Compound | Reactivity | Price/kg | Storage Stability |
---|---|---|---|
4-Bromo-3-chloropyridine | High | $850-920 | 12 months |
2-Chloro-5-bromopyridine | Medium | $780-850 | 9 months |
"Achieved 92% yield in palbociclib intermediate synthesis through optimized coupling reactions."
"Reduced production costs by 18% while maintaining 99.5% purity in neonicotinoid derivatives."
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