3-HYDROXY-4-PYRIDINECARBOXYLIC ACID

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3-HYDROXY-4-PYRIDINECARBOXYLIC ACID: Ultimate Buyer’s Guide (2024)

Table of Contents

1. Product Overview & Specifications

Parameter 3-Hydroxy-4-pyridinecarboxylic Acid Typical Industry Standard
CAS Number 10349-57-2
Molecular Formula C6H5NO3
Purity Grade ≥99% (HPLC) ≥97%
Melting Point 280-283°C (dec.) 270-285°C
Solubility 50 mg/mL in DMSO 30-40 mg/mL

2. Key Applications & Industrial Uses

Pharmaceutical Intermediate

Critical component in synthesis of:

  • Antibacterial agents targeting Gram-positive pathogens
  • Neurological disorder therapeutics
  • Metal-chelating drug formulations

Chemical Research

  • Ligand in transition metal catalysis
  • Building block for supramolecular chemistry

3. Performance Comparison with Alternatives

Feature 3H4PCA 2-Hydroxynicotinic Acid 4-Pyridinecarboxylic Acid
Thermal Stability Excellent Good Moderate
Metal Chelation Capacity High (log β 8.2) Medium (log β 6.8) Low

4. Operational Best Practices

Storage Guidelines

  • Maintain at 2-8°C in sealed containers
  • Argon atmosphere for long-term storage

Reaction Optimization

  • Optimal pH range: 6.5-7.5
  • Recommended solvent systems: DMF/H2O (3:1)

5. Real-World Case Studies

Case 1: Pharmaceutical Manufacturer (Shanghai)

  • Application: Antibiotic intermediate synthesis
  • Result: 22% yield improvement vs previous process
  • Purity Achieved: 99.7%

Case 2: Catalysis Research Lab (Germany)

  • Application: Asymmetric hydrogenation catalyst
  • Result: 91% enantiomeric excess achieved

6. Technical Support & Purchasing

Contact our chemistry experts for:

  • Custom synthesis options
  • Bulk pricing (100kg+ orders)
  • Technical documentation

Contact:
Email: info@vivalr.com
Tel: (86) 15866781826

FAQ

  • Q: Minimum order quantity?
    A: 100g for R&D samples
  • Q: Lead time for bulk orders?
    A: 2-3 weeks after confirmation
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