2-Methoxy-4-pyridinecarboxylic acid

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2-Methoxy-4-pyridinecarboxylic Acid: Comprehensive Product Guide

Contents

1. Product Specifications & Comparative Analysis

Parameter 2-Methoxy-4-pyridinecarboxylic Acid 4-Pyridinecarboxylic Acid 2-Chloro-4-pyridinecarboxylic Acid
CAS Number 40181-98-6 536-23-2 101060-91-7
Molecular Formula C7H7NO3 C6H5NO2 C6H4ClNO2
Molecular Weight 153.14 g/mol 123.11 g/mol 157.56 g/mol
Appearance White crystalline powder Off-white powder Pale yellow crystals
Purity (HPLC) ≥98.5% ≥97% ≥95%

2. Applications & Industrial Uses

Pharmaceutical Development

Acts as critical building block for:

  • Kinase inhibitors (EGFR/VEGFR)
  • Anticancer drug intermediates
  • Antiviral compound synthesis

Agrochemical Formulations

  • Herbicide synergist in crop protection
  • Fungicide metabolite

Chemical Synthesis

  • Ligand for transition metal catalysis
  • Coordination polymer precursor

3. Operational Guidelines

Storage Protocols

  • Temperature: 2-8°C in sealed container
  • Humidity: ≤30% RH

Reaction Compatibility

  • Optimal pH range: 6.5-7.5
  • Compatible solvents: DMF, DMSO, THF

4. Implementation Case Studies

Case 1: Pharmaceutical API Synthesis

Challenge: Improve yield of tyrosine kinase inhibitor intermediate
Solution: Used as directing group in Suzuki coupling
Result: 22% yield increase with 99.2% enantiomeric excess

Case 2: Agricultural Formulation

Challenge: Reduce phytotoxicity in herbicide
Solution: Structural modification via methoxy group
Result: 40% lower EC50 value achieved

5. Client Success Stories

PharmaCorp Ltd. (Shanghai, China)

Application: Third-generation EGFR inhibitor development
Scale: 150 kg/month production
Outcome: Successful IND submission with 98.7% purity

AgroScience GmbH (Berlin, Germany)

Application: Next-gen fungicide formulation
Technical Support: Customized particle size optimization (D90 ≤50μm)
Benefit: 30% improvement in field efficacy

6. Request Customized Solutions

Contact our technical team for:

  • Bulk quantities (100kg+ orders)
  • GMP-grade synthesis
  • Custom derivatization services

Email: info@vivalr.com
Tel: (86) 15866781826

Why Choose Us?

  • ISO 9001-certified production
  • Batch-to-batch consistency guarantee
  • Technical documentation support (CoA, MSDS, DMF)
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