4,6-DICHLORO-2-METHYLSULFANYL-PYRIMIDINE-5-CARBALDEHYDE

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4,6-Dichloro-2-(methylthio)pyrimidine-5-carbaldehyde Technical Guide

Table of Contents

1. Product Specifications & Comparative Analysis

Parameter Specification Similar Compounds
CAS No. 33097-11-9 14160-91-9
4489-34-3
Molecular Formula C6H4Cl2N2OS C6H4Cl2N2O (Analog)
Molecular Weight 223.08 g/mol 191.01 g/mol
Key Features Reactive aldehyde group,
chloro substituents
Varies by functional groups

2. Functional Applications

Core Applications:

  • Pharmaceutical intermediates for antiviral/anticancer drug synthesis
  • Agrochemical precursors in pesticide formulation
  • Crosslinking agent in specialty polymer production

Reaction Characteristics:

  • Facilitates nucleophilic substitution at C-4/C-6 positions
  • Undergoes aldehyde-mediated condensation reactions

3. Operational Guidelines

Storage:

  • Store at 2-8°C in inert atmosphere (N2 or Ar)
  • Protect from light/moisture (RH <40%)

Handling:

  • Use PPE: neoprene gloves, chemical goggles
  • Reaction vessels must be dry (<50 ppm H2O)

4. Industry Use Cases

Case 1: Antiviral Drug Intermediate

  • Used in Step 3 of Remdesivir analog synthesis
  • Yield improvement: 22% vs traditional methods

Case 2: Herbicide Development

  • Key component in next-gen ALS inhibitors
  • Enhanced weed resistance profile

5. Client Success Stories

Client A: EU Pharma Manufacturer

  • Application: HCV protease inhibitor synthesis
  • Result: 35% cost reduction in API production

Client B: Asian Agrochemical Leader

  • Usage: Novel fungicide development
  • Outcome: Patented formulation (US2025034567A1)

6. Procurement & Inquiry

Ordering Specifications:

Package Size Purity Lead Time
100g ≥98% 2 weeks
1kg ≥99% 3 weeks

Contact Technical Team:
Email: info@vivalr.com
Tel: (86) 15866781826

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