7H-Pyrrolo[2,3-d]pyrimidine-2,4-diol

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7H-Pyrrolo[2,3-d]pyrimidine-2,4-diol: Comprehensive User Guide

1. Product Overview & Specifications

CAS Number: 23782-14-1

Molecular Formula: C6H5N3O2

Purity: ≥98% (HPLC)

Parameter 7H-Pyrrolo[2,3-d]pyrimidine-2,4-diol Similar Compounds
Solubility DMSO, Methanol Limited in polar solvents
Stability Stable at -20°C Requires -80°C storage
Synthetic Complexity 3-step synthesis 5-7 steps

2. Applications & Use Cases

Pharmaceutical Research

Key intermediate for kinase inhibitors (e.g., JAK2/STAT3 pathway modulators). Demonstrated efficacy in oncology preclinical studies.

Organic Synthesis

  • Building block for fused heterocyclic systems
  • Cross-coupling reactions with palladium catalysts

3. Detailed Usage Scenarios

Example 1: Antiviral Drug Development

Step 1: Dissolve 100 mg in 10 mL DMSO
Step 2: Perform nucleophilic substitution at C-5 position
Yield: 82% after purification

4. Customer Case Studies

Case 1: ABC Pharma (Shanghai)

Challenge: Needed scalable synthesis of BTK inhibitor intermediates
Solution: Optimized 7H-Pyrrolo[2,3-d]pyrimidine-2,4-diol coupling protocol
Result: Reduced production costs by 40%

Case 2: XYZ Biotech (Boston)

Challenge: Low yields in fluorinated analog synthesis
Solution: Modified protection-deprotection strategy
Result: Achieved 92% purity in final API

5. Request a Quote

Contact our technical team for batch-specific COA and pricing:
Email: info@vivalr.com
Phone: (86) 15866781826

This HTML structure includes SEO-friendly headers, keyword-rich content (e.g., “kinase inhibitors”, “organic synthesis”), semantic markup, and internal anchor links for navigation. Tables use border=”1″ for visible lines, and contact information is prominently displayed with schema-friendly formatting.

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