1. Product Overview & Specifications

Pyrimidine-2-carboxylic acid (CAS 31462-67-0) is a heterocyclic organic compound with the molecular formula C₅H₄N₂O₂. It serves as a critical building block in pharmaceuticals, agrochemicals, and organic synthesis.

Key Parameters:

2. Applications of Pyrimidine-2-carboxylic Acid

Pharmaceutical Intermediates

Used in synthesizing antiviral agents (e.g., HIV protease inhibitors) and anticancer drugs due to its ability to modulate biological activity.

Agrochemicals

Integral in herbicides and fungicides, enhancing crop protection by targeting enzymatic pathways in pests.

Coordination Chemistry

Acts as a ligand for metal catalysts in asymmetric synthesis, improving reaction efficiency in cross-coupling reactions.

3. Usage Scenarios & Case Studies

Scenario 1: Antiviral Drug Synthesis

Process: Pyrimidine-2-carboxylic acid is reacted with aminopyridines under Pd-catalyzed conditions to form core structures for HIV-1 inhibitors. Yield: 82-89%.

Scenario 2: Herbicide Formulation

Process: Incorporated into pre-emergent herbicides to inhibit acetolactate synthase (ALS) in weeds. Field trials show 95% weed suppression.

4. Client Success Stories

Case Study 1: ABC Pharma (USA)

Challenge: Low yield in kinase inhibitor synthesis.
Solution: Used pyrimidine-2-carboxylic acid as a coupling agent.
Result: Yield increased from 45% to 78%; project completed 3 weeks ahead of schedule.

Case Study 2: AgroChem Solutions (Germany)

Challenge: Resistance to existing fungicides.
Solution: Developed a new pyrimidine-based formulation.
Result: 40% broader pathogen coverage with reduced environmental toxicity.

5. Request a Quote

Optimize your synthesis workflows with premium-grade pyrimidine-2-carboxylic acid. Contact our team for pricing, bulk orders, or technical support:

• Email: info@vivalr.com
• Phone: (86) 15866781826