2-Hydroxy-5-nitronicotinic acid

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2-Hydroxy-5-nitronicotinic Acid: Comprehensive User Guide

1. Product Overview & Specifications

2-Hydroxy-5-nitronicotinic acid (CAS 6164-79-0) is a high-purity nitro-substituted nicotinic acid derivative with molecular formula C₆H₄N₂O₅ and molecular weight 184.11 g/mol.

Parameter Specification Competitor A Competitor B
Purity ≥99.5% 98.0-99.0% 97.5-98.5%
Melting Point 268-270°C 265-268°C 263-267°C
Solubility DMSO, DMF Partial in DMSO Limited solubility

2. Key Applications & Industrial Uses

Pharmaceutical Intermediate

Essential for synthesizing anti-tuberculosis agents and kinase inhibitors.

Coordination Chemistry

Forms stable complexes with transition metals (Cu²⁺, Fe³⁺) for catalytic systems.

Agrochemical Development

Key precursor for nitration reactions in herbicide formulations.

3. Operational Guidelines & Safety

  • Storage: Maintain at 2-8°C in amber glass containers
  • Handling: Use nitrile gloves and chemical goggles
  • Incompatibilities: Avoid strong oxidizers & bases

4. Performance Comparison

Feature Our Product Industry Average
Reaction Yield 92-95% 85-88%
Byproduct Formation <3% 5-8%

5. Real-World Case Studies

Case 1: Innovate Pharma Solutions

Application: Synthesis of novel EGFR inhibitors
Result: Achieved 89% yield improvement vs. previous intermediates

Case 2: EuroAgro Chemicals

Application: Development of soil-stable herbicides
Result: 40% reduction in nitro-group decomposition

6. Request Customized Solutions

Contact our technical team for batch-specific COA or formulation support:

Email: info@vivalr.com
Tel: +86 158 6678 1826

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