3,5-Difluoropyridine User Guide: Applications, Case Studies, and Technical Specifications
Table of Contents
1. Product Overview & Technical Specifications
3,5-Difluoropyridine (CAS 103039-62-7) is a fluorinated heterocyclic compound with molecular formula C5H3F2N. Key parameters:
| Parameter | Specification | Comparison with Pyridine |
|---|---|---|
| Molecular Weight | 115.08 g/mol | 18% lighter |
| Purity | ≥99.5% (HPLC) | Higher fluorination stability |
| Melting Point | -12°C to -10°C | Improved solubility |
| Storage | 2-8°C in inert gas | Similar handling requirements |
2. Key Applications of 3,5-Difluoropyridine
Pharmaceutical Intermediates
Widely used in synthesis of:
- Kinase inhibitors (e.g., EGFR inhibitors)
- Anticancer drug candidates
- Neuropharmaceutical precursors
Agrochemicals
- Key component in next-gen fungicides
- Herbicide potency enhancer
3. Operational Guidelines
Handling Protocols
- Use PPE including fluoropolymer gloves
- Maintain nitrogen atmosphere during transfer
- Store in amber glass containers
4. Industry Case Studies
Case 1: Pharmaceutical Synthesis
Challenge: Improve solubility of EGFR inhibitor
Solution: Used as directing group in palladium-catalyzed coupling
Outcome: 40% yield improvement vs non-fluorinated analog
5. Client Success Stories
Client A: Top 10 Pharma Company
Project: Development of PARP inhibitor
Usage: 15kg in preclinical trials
Result: Achieved 98.7% purity in final API
Client B: Agrochemical Leader
Application: Systemic fungicide formulation
Benefit: 30% field efficacy increase
6. Request Customized Solutions
Contact our technical team for:
- Bulk pricing (100kg+ orders)
- Custom fluorination services
- GMP-grade manufacturing
Email: info@vivalr.com
Tel: (86) 15866781826
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