4-Hydroxy-6-methylpyrimidine Technical Guide
Table of Contents
1. Chemical Identification & Specifications
| Parameter | Specification | Comparison with Analogues |
|---|---|---|
| CAS Number | 3524-87-6 | vs 3977-29-5 (amino derivative) |
| Molecular Formula | C5H6N2O | Simpler structure than ethirimol (C11H19N3O) |
| Molecular Weight | 110.11 g/mol | Lower MW than dimethirimol (224.29 g/mol) |
| Purity Grade | ≥98% (HPLC) | Research-grade vs industrial-grade variants |
2. Applications & Industrial Uses
Core Functions:
- Pharmaceutical intermediate for carboxamide synthesis
- Building block for agrochemical compounds
- Reference standard in analytical chemistry
- Precursor in fungicide development
Industry-Specific Applications:
- Agrochemicals: Key component in systemic fungicides
- Pharmaceuticals: Intermediate for carbonic anhydrase inhibitors
- Research: Used in structure-activity relationship studies
3. Handling & Safety Protocols
| Hazard Code | Risk Statement | Preventive Measures |
|---|---|---|
| H302 | Harmful if swallowed | Use fume hood, avoid ingestion |
| H318 | Causes serious eye damage | Wear safety goggles face shield |
First Aid Measures:
- Eye Contact: Flush with water ≥15 minutes
- Ingestion: Rinse mouth, seek medical attention
- Storage: Keep in cool dry place (2-8°C)
4. Industry Application Cases
Case 1: Fungicide Formulation
Used in development of milcurb analogues showing 92% efficacy against powdery mildew in wheat crops
Case 2: Pharmaceutical Intermediate
Served as chiral building block in synthesis of ocular hypertension medication (patent EP296879)
5. Client Success Stories
AgroResearch Ltd. (2024)
Improved crop protection formula using 4-Hydroxy-6-methylpyrimidine derivatives reduced fungicide dosage by 40%
PharmaSynth Inc. (2023)
Developed novel carbonic anhydrase inhibitor using this compound as key intermediate, now in Phase II trials
University Research Team (2022)
Published 3 peer-reviewed papers on structure-activity relationships using this chemical as model compound


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