IMIDAZO[1,2-A]PYRIMIDINE-2-CARBOXYLIC ACID ETHYL ESTER

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IMIDAZO[1,2-A]PYRIMIDINE-2-CARBOXYLIC ACID ETHYL ESTER: Comprehensive User Guide

1. Product Overview & Specifications

IMIDAZO[1,2-A]PYRIMIDINE-2-CARBOXYLIC ACID ETHYL ESTER (CAS: 1003740-89-7) is a high-purity heterocyclic compound widely used in pharmaceutical intermediates and organic synthesis.

Parameter Specification Competitor A Competitor B
Purity ≥98.5% ≥97% ≥96%
Molecular Weight 221.22 g/mol 221.22 g/mol 221.22 g/mol
Solubility DMSO, Ethanol DMSO only Limited
Storage 2-8°C (dry) Room Temp 2-8°C

2. Key Applications

  • Intermediate for kinase inhibitors in oncology research
  • Building block for antiviral drug development
  • Precursor in fluorescent probe synthesis

3. Usage Guidelines

Typical Reaction Conditions:
– Concentration: 0.1-0.5 M in DMSO
– Temperature: 25-80°C
– Reaction Time: 4-24 hours

Safety Protocols:
Use PPE and conduct reactions under inert atmosphere when handling sensitive substrates.

4. Case Studies

Case 1: Optimized synthesis of Bruton’s tyrosine kinase (BTK) inhibitor using 15% reduced catalyst loading.
Case 2: Improved yield (82% → 91%) in nucleoside analogue production through modified coupling protocol.

5. Client Success Stories

PharmaCorp Ltd.: Achieved 40% faster API development for Phase III trial by implementing our optimized synthesis route.
BioResearch Inc.: Reduced impurity levels from 2.1% to 0.3% in antiviral candidate batches.
ChemSolutions AG: Scaled production to 50kg batches with 99.2% consistency across 12 consecutive runs.

6. Contact for Custom Solutions

Request technical documents or discuss bulk orders:
info@vivalr.com
(86) 15866781826

All compounds manufactured under ISO 9001:2015 certified processes

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