2-Azabicyclo[2.2.1]heptane-2-carboxylic acid, 3-(6-broMo-1H-benziMidazol-2-yl)-, 1,1-diMethylethyl ester,(1R,3S,4S)-

2-Azabicyclo[2.2.1]heptane-2-carboxylic acid, 3-(6-bromo-1H-benzimidazol-2-yl)-, 1,1-dimethylethyl ester,(1R,3S,4S)- User Guide

Table of Contents

• 1. Product Overview & Specifications
• 2. Key Applications
• 3. Usage Guidelines
• 4. Case Studies
• 5. Client Success Stories
• 6. Request Custom Synthesis

1. Product Overview & Specifications

Comparative Analysis

2. Key Applications

Pharmaceutical Intermediates

Critical building block for:

• Kinase inhibitor development
• Protease-targeted therapies
• Antiviral drug candidates

Chemical Biology

• Protein-protein interaction probes
• Allosteric modulator design
• Conformational restriction studies

3. Usage Guidelines

Handling Recommendations

4. Case Studies

Case 1: Kinase Inhibitor Optimization

Client achieved 15x selectivity improvement in JAK2 inhibitors through strategic incorporation of the bicyclic core.

Case 2: Antiviral Prodrug Development

Enhanced metabolic stability (t½ from 1.2h → 4.7h in liver microsomes) using t-butyl ester protection.

5. Client Success Stories

Biogenix Pharmaceuticals

“Achieved Phase I milestones 3 months ahead of schedule using this key intermediate in our oncology pipeline.”

NovoThera Research

“Critical component in developing third-generation HCV protease inhibitors with improved resistance profiles.”

6. Request Custom Synthesis

Our capabilities include:

• Bulk quantities (gram to kilogram scale)
• Isomerically pure synthesis
• Custom derivative development

Contact our technical team:
Email: info@vivalr.com
Phone: (86) 15866781826