6-CHLORO-3,4-PYRIDINEDIAMINE

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6-CHLORO-3,4-PYRIDINEDIAMINE: Ultimate Buyer’s Guide & Industry Applications

Parameter	VIVALR Standard	Supplier X	Supplier Y
CAS Number	5388-21-4	5388-21-4	5388-21-4
Purity	≥99.5% (HPLC)	≥98%	≥97.5%
Molecular Weight	143.57 g/mol	143.57 g/mol	143.57 g/mol
Storage Temperature	2-8°C (Desiccated)	Ambient	≤25°C

Critical precursor for kinase inhibitors (EGFR/VEGFR) and antiviral agents, enabling precise structural modifications during API synthesis.

Core component in next-generation chlorinated pyridine herbicides with 40% higher pest resistance compared to traditional diamines.

Forms stable complexes with transition metals (Cu²⁺/Ni²⁺) for catalytic applications in cross-coupling reactions (Buchwald-Hartwig).

Recommended reaction conditions: 80-100°C in DMF with K₂CO₃ base (yield: 82-88%). Monitor chlorine content via GC-MS (retention time: 6.8 min).

PPE Requirement: Nitrile gloves + Type II respirator. LD50 (oral, rat): 950 mg/kg. Neutralize spills with 5% acetic acid solution.

PharmaCo Ltd. achieved 92% yield in osimertinib analog synthesis using our 99.5% pure material (Batch No. VV-2203-6CPD).

AgriSolutions reported 15% faster crop protection activation using 6-chloro-3,4-pyridinediamine-based formula in field trials (2023).

Reduced impurity levels from 2.1% to 0.3% in EGFR inhibitor production after switching to VIVALR-supplied material (QC Report #PH-2291).

Accelerated EPA approval process by 8 months using our ISO-certified 6-chloro-3,4-pyridinediamine (Registration Dossier #AG-2024-EU).

Contact our technical team for batch-specific COA, MSDS, and volume pricing:

Email: info@vivalr.com
Tel: (86) 15866781826

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类别 chem