Thiophene-2-sulfonamide: Technical Specifications, Applications, and Regulatory Information
Table of Contents
1. Basic Specifications & Comparative Analysis
| Parameter | Thiophene-2-sulfonamide | Generic Sulfonamides |
|---|---|---|
| CAS Number | 6339-87-3 | Varies |
| Molecular Formula | C4H5NO2S2 | R-SO2NH2 |
| Molecular Weight | 163.22 g/mol | 120-300 g/mol |
| Melting Point | 137-148°C | 155-280°C |
| Density | 1.51-1.61 g/cm³ | 1.3-1.8 g/cm³ |
| HS Code (Canada) | 2935000000 | 2935.00.00 |
2. Functional Applications
- Pharmaceutical Intermediates: Key precursor in sulfa drug synthesis
- Electrolyte Stabilizers: Enhances performance in high-voltage LiNi0.8Mn0.1Co0.1O2 battery systems
- Organic Synthesis: Building block for heterocyclic compounds
- Analytical Chemistry: Reference standard in chromatography
3. Operational Guidelines
- Storage: Maintain at room temperature (15-25°C) in sealed containers
- Solubility: Use methanol as primary solvent (25mg/ml)
- Safety Protocols:
- PPE Requirement: Nitrile gloves + ANSI Z87.1 eye protection
- Ventilation: ≥4 air changes/hour in handling areas
- Incompatibilities: Avoid strong oxidizers & concentrated acids
4. Industry Use Cases
| Industry | Application | Performance Benefit |
|---|---|---|
| Pharmaceuticals | Antimicrobial agent synthesis | 30% yield improvement vs traditional methods |
| Energy Storage | High-voltage battery electrolytes | 15% cycle life extension |
| Materials Science | Polymer modification | Thermal stability ≥220°C |
5. Client Implementation Examples
Case 1: Major Battery Manufacturer (Guangzhou)
Challenge: Cycle life degradation in 4.4V NMC batteries
Solution: 0.5wt% 2-TS electrolyte additive
Outcome: 200+ cycles at 80% capacity retention
Case 2: Pharmaceutical Research Institute (Shanghai)
Challenge: Low-yield sulfonamide derivative synthesis
Solution: Optimized reaction with 2-thiophenesulfonamide
Outcome: 92% purity at pilot scale
Technical Consultation
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