Pyrrolo[2,3-d]pyrimidin-4-ol

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Pyrrolo[2,3-d]pyrimidin-4-ol: Comprehensive Guide for Researchers & Buyers

Table of Contents

1. Product Overview & Key Specifications

Parameter Specification
CAS Number 16357-71-8
Molecular Formula C₆H₅N₃O
Molecular Weight 135.13 g/mol
Purity ≥98% (HPLC)
Appearance Off-white to pale yellow crystalline powder
Storage 2-8°C in sealed container

2. Applications in Pharmaceutical Research

Widely used as:

  • Core scaffold for kinase inhibitor development
  • Intermediate in anticancer drug synthesis
  • Building block for JAK/STAT pathway modulators

3. Usage Scenarios & Industry Case Studies

3.1 Kinase Profiling Studies

Used in high-throughput screening for EGFR inhibitors (IC₅₀ optimization)

3.2 Oncology Research

Key component in PD-1/PD-L1 pathway inhibitor development

4. Technical Comparison: Supplier Analysis

Vendor Purity Price/Gram Lead Time
Vivalr Chem 99.2% $220 2 weeks
Vendor B 97.8% $280 6 weeks
Vendor C 95.5% $195 8 weeks

5. Client Success Stories

Case 1: PharmaTech Solutions

Application: Developed novel BTK inhibitor using our batch #PT-2290 material

Result: Achieved 83% tumor growth inhibition in preclinical models

Case 2: BioKinetics Research

Application: SAR study for CDK4/6 inhibitors

Result: Identified lead compound with 15x selectivity improvement

6. Procurement Support & Custom Solutions

Contact our technical team for:

  • Bulk pricing (50g+ orders)
  • Custom purity requirements (up to 99.9%)
  • Stable isotope-labeled derivatives

Email: info@vivalr.com
Phone: (86) 15866781826

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