3,5-Lutidine

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3,5-Lutidine (3,5-Dimethylpyridine) Technical Overview

1. Chemical Properties & Specifications

Parameter Value
CAS No. 591-22-0
Molecular Formula C7H9N
Molecular Weight 107.15–107.16 g/mol
Appearance Colorless liquid with pungent odor
Melting Point -12°C to -6.6°C
Boiling Point 163°C–172°C
Density 0.939–0.95 g/cm3 at 25°C
Flash Point 2°C–53°C (variable by purity)
Solubility Miscible in ethanol/ether; 33 g/L in water (20°C)
Refractive Index n20/D: 1.504–1.506

2. Industrial Applications

Core Uses:

  • Pharmaceutical intermediates (antihypertensive agents, vitamin B3 derivatives)
  • Surfactant synthesis (quaternary ammonium compounds)
  • Coordination chemistry solvent for organometallic reactions
  • Precursor for agrochemicals and corrosion inhibitors

3. Operational Guidelines

Reaction Conditions:

  • Optimal temperature range: 50°C–150°C
  • Inert atmosphere (N2/Ar) recommended for oxidation-sensitive reactions
  • Compatible with Grignard reagents and transition metal catalysts

4. Safety Protocols

Hazard Precaution
Flammability Class IB flammable liquid (NFPA 704: Health 2, Flammability 3)
Reactivity Incompatible with strong oxidizers, acids, and acid chlorides
Health Risks
  • Central nervous system depression
  • Hepatorenal toxicity (TLV-TWA: 2 ppm)
  • Severe eye irritation (wear safety goggles)

5. Storage & Transportation

  • UN No.: 1993
  • Packaging Group: III
  • Storage Temp: 2°C–8°C under nitrogen blanket
  • Transport: Ground shipping only (DOT/ADR certified containers)

6. Regulatory Compliance

  • REACH Registration: 01-2119487322-38-XXXX
  • SARA 313: Not regulated
  • California Prop 65: No listed carcinogens

Technical Support: For material specifications or COA requests, contact:
Email: info@vivalr.com
Tel: (86) 15866781826 (24/7 Emergency Response)

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