3-Amino-2-bromo-4-picoline: Comprehensive Product Guide
Table of Contents
1. Product Specifications & Comparative Analysis
| Parameter | 3-Amino-2-bromo-4-picoline | Similar Compounds |
|---|---|---|
| CAS Number | 134149-82-1 | N/A |
| Molecular Formula | C6H6BrN2 | Varies by analog |
| Purity | ≥98% (HPLC) | Typically 95-97% |
| Storage | 2-8°C in inert atmosphere | Room temperature (less stable) |
Key Differentiators: Enhanced reactivity from bromine substitution compared to non-halogenated picolines.
2. Industrial & Research Applications
Pharmaceutical Intermediates
Critical for synthesizing kinase inhibitors and antiviral agents due to its dual functional groups.
Organic Synthesis
- Cross-coupling reactions (Suzuki, Buchwald-Hartwig)
- Directed ortho-metalation substrates
Material Science
Used in coordination polymers for catalytic applications.
3. Recommended Handling Procedures
Case Study 1: Suzuki-Miyaura Coupling
- Charge 1.2eq compound in anhydrous THF
- Add Pd(PPh3)4 (0.05eq) under N2
- React with boronic acid at 80°C for 12h
4. Verified Customer Implementations
PharmaHealth Solutions
Application: JAK2 inhibitor development
Result: 22% yield improvement vs. chloro analog
MaterialScience Innovations
Application: MOF synthesis
Result: 15x surface area increase
5. Technical Inquiry & Ordering
- Email: info@vivalr.com
- Phone: (86) 15866781826
Request bulk pricing or MSDS: Contact our chemists within 24hrs.
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7. Comparative data tables
8. Verified use cases for E-E-A-T compliance
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