| Parameter | 4-Hydroxy-6-aminopyrimidine | 4-Aminopyrimidine | 6-Hydroxypyrimidine |
|---|---|---|---|
| CAS Number | 5467-70-9 | 1072-86-4 | 1004-41-5 |
| Molecular Formula | C4H5N3O | C4H5N3 | C4H4N2O |
| Purity Grade | ≥99% (Pharmaceutical Grade) | ≥97% (Industrial Grade) | |
| Thermal Stability | Stable up to 250°C | Decomposes at 180°C | Decomposes at 160°C |
Critical component in synthesizing kinase inhibitors (e.g., EGFR inhibitors) and antiviral agents. Enables precise molecular modifications in lead compound optimization.
Key precursor for systemic herbicides and fungicides with enhanced plant mobility and residual activity. Compatible with modern slow-release formulations.
Building block for conductive polymers and coordination complexes in organic electronics. Enables π-π stacking in supramolecular architectures.
| Parameter | Specification |
|---|---|
| Storage Temperature | 2-8°C (desiccated environment) |
| Solubility Profile | DMSO: 50 mg/mL Water: <1 mg/mL (pH dependent) |
| Incompatible Materials | Strong oxidizers, acid chlorides |
Challenge: Achieve selective kinase inhibition in triple-negative breast cancer models
Solution: Structural modification using 4-Hydroxy-6-aminopyrimidine core
Outcome: 78% tumor growth inhibition vs control in Phase II preclinical trials
Challenge: Overcome glyphosate resistance in Palmer amaranth
Solution: Novel auxin mimic formulation using hydroxyaminopyrimidine derivatives
Outcome: 92% weed control efficacy at reduced application rates
"Integration of 4-Hydroxy-6-aminopyrimidine reduced our lead compound synthesis time from 14 to 6 days while improving yield consistency from 65% to 89%."
"Our soil persistence studies showed 40% longer residual activity compared to traditional pyrimidine analogs, significantly reducing seasonal application frequency."
For batch-specific COA, custom synthesis projects, or bulk pricing:
Email: info@vivalr.com
Tel: (86) 15866781826
Request free sample (1-5g available for R&D verification):
[Specify required purity grade and application purpose]
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