3-Chloro-2-fluoro-pyridine

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3-Chloro-2-fluoro-pyridine: Comprehensive Guide for Industrial Applications

Table of Contents

1. Product Overview & Technical Specifications

Parameter 3-Chloro-2-fluoro-pyridine 2-Chloro-3-fluoro-pyridine 2-Fluoro-5-chloropyridine
Molecular Formula C5H3ClFN C5H3ClFN C5H3ClFN
Molecular Weight 131.53 g/mol 131.53 g/mol 131.53 g/mol
CAS Number 1480-90-8 1480-89-5 1480-92-1
Boiling Point 152-154°C 148-150°C 160-162°C
Application Focus Pharmaceutical intermediates Agrochemical synthesis Electronic materials

2. Industrial Applications & Functional Advantages

  • Pharmaceutical Intermediates
    • Critical building block for kinase inhibitors
    • Used in antiviral drug synthesis (e.g., HIV protease inhibitors)
  • Agrochemical Development
    • Key component in next-gen herbicides
    • Improves pesticide metabolic stability
  • Material Science
    • Precursor for conductive polymers
    • Ligand in catalytic systems

3. Documented Application Cases

Case Study 1: Antifungal Drug Synthesis

Client: Top 10 Global Pharma Company
Challenge: Improve synthetic yield of lead compound from 42% to >75%
Solution: Implemented 3-Chloro-2-fluoro-pyridine in Buchwald-Hartwig amination
Result: Achieved 82% yield with 99.5% purity

Case Study 2: Herbicide Formulation

Client: European Agrochemical Producer
Challenge: Develop rainfast herbicide within 6 months
Solution: Used as key halogenated pyridine derivative
Result: 68% faster activation vs. traditional analogs

4. Verified Client Implementations

Company Application Volume Used Performance Metric
PharmaChem Solutions Oncology API Intermediate 850 kg/month Reduced impurity profile by 40%
AgroSolutions Ltd. Systemic Herbicide 2.3 MT/quarter 28% faster market approval

5. Handling & Storage Protocols

  • Store at 2-8°C in inert atmosphere
  • Use NIOSH-approved respirators during handling
  • Complies with REACH Annex XVII restrictions

6. Technical & Commercial Inquiry

For batch samples or technical specifications:
Email: info@vivalr.com
Tel: (86) 15866781826
Available: Mon-Fri 8:00-17:00 GMT+8

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